Methods of obtaining histidine-rich protein genes of Plasmodia,

Details Methods of obtaining histidine-rich protein genes of Plasmodia, Methods of obtaining histidine-rich protein genes of Plasmodia,

1986-08-26

1992-05-26

Kepplinger, Esther L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 6, 435 691, 435 91, 4351723, 435814, 435849, 436501, 530358, 530802, 530825, 935 12, 935 18, 935 19, 935 29, 935 47, 935 55, 935 72, 935 78, C07H 2104, C07K 1300, C12Q 168, G01N 3368

Patent

active

051169657

ABSTRACT:
A method for obtaining DNA expressing histidine rich protein of various types of Plasmodia is disclosed. The method involves hybridization with the comparable DNA of P. lophurae. The method of particularly well suited for obtaining P. falciparum DNA, whether it is associated with know or knobless phenotype. Additionally, the invention disclosed a safe method for diagnosing P. falciparum infection.

REFERENCES:
Ravetch et al. (1984) Nature vol. 312, pp. 616-620.
Wallach et al. (1984) Molecular and Biochemical Parasitology, vol. 12, pp. 85-94.

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