Lawsonia intracellularis subunit vaccine

Details Lawsonia intracellularis subunit vaccine Lawsonia intracellularis subunit vaccine

2004-09-08

2010-02-16

Mondesi, Robert B (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Amino acid sequence disclosed in whole or in part; or...

Reexamination Certificate

active

07662390

ABSTRACT:
The present invention relates to nucleic acid sequences encoding novelLawsonia intracelluarisproteins. It furthermore relates to DNA fragments, recombinant DNA molecules and live recombinant carriers comprising these sequences. Also it relates to host cells comprising such nucleic acid sequences, DNA fragments, recombinant DNA molecules and live recombinant carriers. Moreover, the invention relates to proteins encoded by these nucleotide sequences and to their use for the manufacturing of vaccines. The invention also relates to vaccines for combatingLawsonia intracellulairsinfections and methods for the preparation thereof. Finally the invention relates to diagnostic tests for the detection ofLawsonia intracellularisDNA, the detection ofLawsonia intracellularisantigens and of antibodies againstLawsonia intracellularis.

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Gebhart, C.J., et al. “Genomic Sequence Survey ofLawsonia intracellularis, the causative agent of proliferative. . .” Database EMBL, Oct. 24, 2002, EMBL accession No. BH795495.

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