Method of controlling a drug release rate

Details Method of controlling a drug release rate Method of controlling a drug release rate

2006-02-07

2010-02-23

Chen, Bret (Department: 1792)

Coating processes

Medical or dental purpose product; parts; subcombinations;...

Implantable permanent prosthesis

C427S002250, C427S523000, C427S524000, C623S001120, C424S422000, C424S426000

Reexamination Certificate

active

07666462

ABSTRACT:
A method of controlling the drug release rate of a drug coated endovascular stent by depositing a drug material layer on the stent and then modifying the drug material using gas cluster ion beam irradiation to create a carbon matrix with interstices containing the original drug. The rate at which the drug elutes through the interstices can be controlled by processing parameters. Multiple layers may be employed to create time varying release rates.

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