siRNA targeting myeloid differentiation primary response...

Details siRNA targeting myeloid differentiation primary response... siRNA targeting myeloid differentiation primary response...

2007-10-30

2010-02-16

Chong, Kimberly (Department: 1635)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S024310, C536S024100, C435S006120, C435S325000, C435S375000, C514S04400A

Reexamination Certificate

active

07662950

ABSTRACT:
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for MYD88.

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Hammond et al. Post-transcriptional gene silencing by double-stranded RNA Nature Reviews, 2001, vol. 2, 110-119. MacMillan Magazines Ltd.

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