Enrichment through heteroduplexed molecules

Details Enrichment through heteroduplexed molecules Enrichment through heteroduplexed molecules

2007-12-28

2010-12-14

Whisenant, Ethan (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S091200, C536S022100, C536S023100, C536S024300

Reexamination Certificate

active

07851158

ABSTRACT:
The present invention relates to the enrichment of specific target sequences. Enrichment can be achieved through the formation of a heteroduplex that includes the specific target sequence and then the specific cleavage of the heteroduplex. A binding moiety is then added to the cleaved heteroduplex, allowing for the subsequent manipulation of the specific target sequence in the heteroduplex.

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