Pharmaceutical composition and method for treating cardiovascula

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514255, 514601, 514613, 514617, 514608, 564182, A01N 4300, A01N 4360, A01N 4106, A01N 3718

Patent

active

051168510

ABSTRACT:
A novel pharmaceutical composition and method is disclosed for the treatment of cardiovascular diseases, e.g. myocardial ischemia and/or arrhythmia. The method and composition include an effective amount of a compound of the formula ##STR1## wherein X, Y, R, R.sub.1, A, A', m, n, p, p' and B are as defined herein.

REFERENCES:
patent: 3378586 (1968-04-01), Krapcho
patent: 4724235 (1988-02-01), Shanklin et al.
Advances in Drug Research, vol. 16, (Jan. 1987), pp. 379-386, R. A. Janis et al.
G. J. Grover et al., Journal of Cardiovascular Pharmacology, 14:331-340 (Feb. 1989).
J. Krapcho et al., Compounds Related to Thiazesim. III, vol. 11, pp. 361-364, Mar. 1968.

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