Method of treating cancer by administering conjugates...

Drug – bio-affecting and body treating compositions – Lymphokine – Interleukin

Reexamination Certificate

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C514S012200

Reexamination Certificate

active

07736639

ABSTRACT:
Methods of treating cancer in patients in need thereof with human interleukin-18 (IL-18) polypeptides and substitution mutants thereof that are conjugated to water-soluble polymers at specific sites on the human IL-18 protein are disclosed.

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