Methods of treating using hormone-albumin fusion proteins

Details Methods of treating using hormone-albumin fusion proteins Methods of treating using hormone-albumin fusion proteins

2007-10-29

2010-11-16

Landsman, Robert (Department: 1647)

Drug, bio-affecting and body treating compositions

Lymphokine

Interferon

C424S185100, C424S192100, C514S012200, C530S351000, C530S362000

Reexamination Certificate

active

07833521

ABSTRACT:
Biologically active polypeptides comprising a therapeutically active polypeptide fused to human serum albumin or a variant of human serum albumin, methods for preparation, nucleotide sequences encoding such fusion polypeptides, expression cassettes comprising such nucleotide sequences, self-replicating plasmids containing such expression cassettes, and pharmaceutical compositions containing fusion polypeptides.

REFERENCES:
patent: 4881175 (1989-11-01), Ladner
patent: 5374620 (1994-12-01), Clark et al.
Poznansky, Growth hormone-albumin conjugates, 1998, FEBS, vol. 239, No. 1, p. 18-22.
Yeh, 1992, Proc. Natl. Acad. Sci. USA, vol. 89, pp. 1904-1908.

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