Drug diffusion barriers for a catheter assembly

Details Drug diffusion barriers for a catheter assembly Drug diffusion barriers for a catheter assembly

1999-09-27

2010-12-14

Lucchesi, Nicholas D (Department: 3763)

Surgery

Means for introducing or removing material from body for...

Treating material introduced into or removed from body...

Reexamination Certificate

active

07850643

ABSTRACT:
Materials having barrier characteristics are used with a balloon of a catheter assembly and a sheath for covering the balloon. The barrier materials prevent significant absorption of therapeutic substances used in association with the balloon, for example via a medicated prosthesis, into the balloon wall or the sheath. Accordingly the quantity and concentration of the therapeutic substances are preserved. Materials which can serve as a barrier include barrier polymers, polymers with additive fillers, polymers with a metallic coating, metallic films, polymers with a main group element oxide coating, and sulfonated or fluorinated polymers. For the sheath, materials such as glass and metals also function effectively.

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