Method of processing and storing mass spectrometry data

Data processing: measuring – calibrating – or testing – Measurement system in a specific environment – Electrical signal parameter measurement system

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C702S076000, C702S182000, C702S191000, C250S226000, C356S303000, C356S319000

Reexamination Certificate

active

07657387

ABSTRACT:
A data compression technique is disclosed for Fourier Transform Mass Spectrometry (FTMS). A statistical analysis is applied to the data in the frequency domain since most of this data is a result of randomly distributed electronic noise. A fit of the whole frequency dataset to the distribution is made to determine preliminary moments of the distribution. The data in the tail of that distribution (which is mainly the peak data) is then removed and the remaining data points are re-fitted to the distribution, to identify the moments of distribution of that remaining noise data. A noise threshold for the mass spectrum is then applied using the calculated moments. The data above the threshold is kept. The whole spectrum can be reconstituted by storing the moments of distribution along with the peak data and then regenerating the noise from those moments and adding it to the peak data.

REFERENCES:
patent: 4008388 (1977-02-01), McLafferty et al.
patent: 4875169 (1989-10-01), Synovec et al.
patent: 5175430 (1992-12-01), Enke et al.
patent: 5592402 (1997-01-01), Beebe et al.
patent: 5774385 (1998-06-01), Bristol
patent: 5995989 (1999-11-01), Gedcke et al.
patent: 6502045 (2002-12-01), Biagiotti
Grotch, Stanley L., “Computer Identification of Mass Spectra Using Highly Compressed Spectral Codes,” Analytical Chemistry, vol. 45 (No. 1), p. 2-6, (Jan. 1, 1973).
Hanna, D. Alan, “FTMS Noise Characterization,” Proc. ASMS 33rd Annual Conference on Mass Spectrum and Allied Topics, p. 435-436, (May 1, 1985).
Lam, et al., “Clipped Fourier Transform Mass Spectral Compression Algorithm for Microcomputer-compatible Search Systems,” Analytical Chemistry, American Chemical Society (Columbus, US), vol. 53 (No. 11), p. 1679-1684, (Sep. 1, 1981).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method of processing and storing mass spectrometry data does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of processing and storing mass spectrometry data, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of processing and storing mass spectrometry data will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4192919

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.