Pyridone derivative

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S332000, C514S345000, C544S314000, C546S261000, C546S301000

Reexamination Certificate

active

07732456

ABSTRACT:
The invention provides pyridone derivatives represented by a general formula (I)[in the formula, R1and R2may be same or different and stands for H, etc., or R1and R2may form an aliphatic nitrogen-containing heterocyclic group together with the N to which they bind; X1-X3may be same or different and stand for methine or N, provided not all of them simultaneously stand for nitrogen; X4-X7may be same or different and stand for methine or N, provided that three or more of them do not simultaneously stand for N; Y1and Y3may be same or different and stand for single bond, —O—, —NR—, —S—, etc; Y2stands for lower lkylene, etc.; R stands for H, etc., L stands for methylene; Z1and Z2may be same or different and stand for single bond or lower alkylene; or R1, L and Z2may form an aliphatic nitrogen-containing heterocyclic group with the N to which R1binds; and Ar stands for aromatic carbocyclic group, etc.].

REFERENCES:
patent: 6930185 (2005-08-01), Ishihara et al.
patent: 2004/0077628 (2004-04-01), Ishihara et al.
patent: 2005/0176795 (2005-08-01), Schwink et al.
patent: 1 283 199 (2003-02-01), None
patent: WO 01/21577 (2001-03-01), None
patent: WO 02/02744 (2002-01-01), None
patent: WO 02/06245 (2002-01-01), None
patent: WO 02/094799 (2002-11-01), None
patent: WO 03/045912 (2003-06-01), None
patent: WO 03/068230 (2003-08-01), None
Dyke et al., Exp. Opin. Ther. Patents, vol. 15 (2005), pp. 1303-1313, “Recent developments in the discovery of MCH-1R antagonists for the treatment of obesity—an update”.

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