Products for separation applicable to cells in the immunopurific

Chemistry: molecular biology and microbiology – Maintaining blood or sperm in a physiologically active state...

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435 30, 435174, 435177, 435180, 435239, 435243, 604408, 604416, C12N 100, C12N 1100, A61B 1900

Patent

active

051167247

ABSTRACT:
The invention relates to a product to permit separation of cells in the domain of immunopurification and consisting of a finely divided carrier of a density lower than that of the medium from which such cells must be extracted, such carrier being covered with macromolecules capable of being specifically fixed to the cells to be extracted to which a privileged orientation was given to enable fixation of such macromolecules.

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Molday, "Cell Labelling and Separation using Immunospecific Microspheres", in Pretlow et al. (Eds.), Cell Separation, Academic Press, N.Y., 1984, pp. 237-247.
Wormmeester et al, J. Immunol. Methods, 67(2): 389-394 (1984).
R. Y. Stanier et al, The Microbial World, Second Edition, Prentice-Hall, Inc., Englewood Cliffs, N.J., 1963, pp. 139-140, 204.
Biological Abstracts, vol. 78, 1984, ref. no. 19564; J. Wormmeester et al.: "A simple method for immunoselective cell separation with the avidio-biotin system" & J. Immunol Methods 67(2): 389-394 1984 Abstract.
Biological Abstracts, vol. 68, 1979, ref. no. 67642; J. W. Stocker et al.: "Separation of human cells bearing HLA-DR antigens using a monoclonal antibody rosetting method" & Tissue Antigens 3(3), 212-222 1979.
Biological Abstracts, vol. 76, 1983, ref. no. 31400; T. Hoang et al.: "Separation of hemopoietic cells from adult mouse marrow by use of monoclonal antibodies" & Blood 61(3): 580-588, 1983.

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