Chemoprotectants from crucifer seeds and sprouts

Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution... – Containing or obtained from brassica

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S776000

Reexamination Certificate

active

07744937

ABSTRACT:
The present invention is directed to chemoprotectant precursor compositions provided from crucifer seeds and sprouts and methods for their preparation. Treatment of aqueous extracts from crucifer seeds or sprouts with adsorbents substantially increases the ratio of certain highly chemoprotectant precursor compounds (alkyl glucosinolates such as glucoraphanin, a.k.a. sulforaphane glucosinolate) to undesirable compounds such as indole glucosinolates (for example 4-hydroxyglucobrassicin). The method provides an extract which has a ratio of glucoraphanin to 4-hydroxyglucobrassicin of about 70 or greater. The resulting extract has improved color and odor and may be dried or used directly as an additive in a variety of foodstuffs.

REFERENCES:
patent: 4083836 (1978-04-01), Anjou et al.
patent: 5043178 (1991-08-01), Gottesman, deceased et al.
patent: 5077071 (1991-12-01), Strop
patent: 5686108 (1997-11-01), Pusateri et al.
patent: 5725895 (1998-03-01), Fahey et al.
patent: 5882646 (1999-03-01), Pusateri et al.
patent: 5968505 (1999-10-01), Fahey et al.
patent: 5968567 (1999-10-01), Fahey et al.
patent: 6086936 (2000-07-01), Wilson et al.
patent: 6117460 (2000-09-01), Kortschack
patent: 6177122 (2001-01-01), Fahey et al.
patent: 6242018 (2001-06-01), Fahey et al.
patent: 6348220 (2002-02-01), Ribnicky et al.
patent: 6361812 (2002-03-01), Ekanayake et al.
patent: 6436450 (2002-08-01), Omary et al.
patent: 6521818 (2003-02-01), Fahey
patent: 6737441 (2004-05-01), Fahey
patent: 6812248 (2004-11-01), Zhang et al.
patent: 6824796 (2004-11-01), Pusateri et al.
patent: 7303770 (2007-12-01), Fahey et al.
patent: 7371419 (2008-05-01), West et al.
patent: 7402569 (2008-07-01), Fahey
patent: 7407986 (2008-08-01), Gao et al.
patent: 2002/0015722 (2002-02-01), Herzog et al.
patent: 2002/0090405 (2002-07-01), Guthrie et al.
patent: 2002/0147155 (2002-10-01), Foster et al.
patent: 2002/0151505 (2002-10-01), Fahey
patent: 2003/0091518 (2003-05-01), Pauly et al.
patent: 2003/0235634 (2003-12-01), Pusateri et al.
patent: 2004/0001817 (2004-01-01), Giampapa
patent: 2004/0052879 (2004-03-01), Ravagnan et al.
patent: 2004/0133936 (2004-07-01), Rossiter et al.
patent: 2005/0031768 (2005-02-01), Sakai et al.
patent: 2005/0042347 (2005-02-01), Bathurst et al.
patent: 2005/0055744 (2005-03-01), Quiros et al.
patent: 2005/0123560 (2005-06-01), Sinnott
patent: 2006/0003073 (2006-01-01), Etzel et al.
patent: 2006/0020046 (2006-01-01), Goralczyk et al.
patent: 2006/0127996 (2006-06-01), Fahey
patent: 2007/0031581 (2007-02-01), West et al.
patent: 2007/0033675 (2007-02-01), Barten
patent: 2007/0190209 (2007-08-01), Sinnott
patent: 2008/0107792 (2008-05-01), Verhoeyen et al.
patent: 19649952 (1998-06-01), None
patent: 102005033616 (2007-01-01), None
patent: 0 006 654 (1980-01-01), None
patent: 0668026 (1995-08-01), None
patent: 1100340 (2001-05-01), None
patent: 1 219 180 (2002-07-01), None
patent: 1 752 052 (2007-02-01), None
patent: 2005206495 (2005-08-01), None
patent: WO 95/08275 (1995-03-01), None
patent: 19991007240 (1999-02-01), None
patent: 19991020242 (1999-04-01), None
patent: WO/00/01222 (2000-01-01), None
patent: 20001030604 (2000-06-01), None
patent: 20001061163 (2000-10-01), None
patent: 20011091764 (2001-12-01), None
patent: 20021015722 (2002-02-01), None
patent: 20031051313 (2003-06-01), None
patent: 20041073418 (2004-09-01), None
patent: 20051013722 (2005-02-01), None
patent: 20061012213 (2006-02-01), None
patent: 2006/102236 (2006-09-01), None
patent: 20061102236 (2006-09-01), None
patent: 20071094827 (2007-08-01), None
See http://www.polylc.com/—accessed Nov. 2008.
Letter from Richard Peet of Foley & Lardner LLP dated Apr. 18, 2008 to James P. Krueger of Fitch, Even, Tabin & Flannery regarding U.S. Patent Application Publication No. 2007/0031581 A1, (1 page).
Cecil H. VanEtten, Clara E. McGrew, and Melvin E. Daxenbichler, “Glucosinolate Determination in Cruciferous Seeds and Meals by Measurement of Enzymatically Released Glucose,” Journal of Agricultural and Food Chemistry, vol. 22, No. 3, 1974, pp. 483-487.
Fahey J.W. et al., “Separation and Purification of Glucosinolates From Crude Plant Homogenates By High-Speed Counter-Current Chromatography.” Journal of Chromatography A, vol. 996, No. 1-2, May 2003, pp. 85-93.
Hansen M. et al., “Glucosinolates in Broccoli Stored Under Controlled Atmosphere.” Journal of the American Society of Horticultural Science, vol. 120, No. 6, 1995, pp. 1069-1074.
Kushad Mosbah M. et al., “Variation of Glucosinolates in Vegetable Crops of Brassica Oleracea.” Journal of Agricultural and Food Chemistry, vol. 47, No. 4, Apr. 1999, pp. 1541-1548.
Lewis J. et al., “Glucosinolate Content of Brassica Vegetables: Analysis of Twenty-Four Cultivars of Calabrese.” Food Chemistry, vol. 25, No. 4, 1987, pp. 259-268.
Pereira F. M. V. et al., “Influence of Temperature and Ontogeny of the Levels of Glucosinolates in Broccoli Sprouts and Their Effect on the Induction of Mammalian Phase 2 Enzymes.” Journal of Agricultural and Food Chemistry, vol. 50, No. 21, 2002, pp. 6239-6244.
Vallejo F. et al., “Potential Bioactive Compounds in Health Promotion From Broccoli Cultivars Grown in Spain.” Journal of the Science of Food and Agriculture, vol. 82, No. 11, Sep. 2002, pp. 1293-1297.
Vallejo F. et al., “Total and Individual Glucosinolate Contents in inflorescences of Eight Broccoli Cultivars Grown Under Various Climatic and Fertilisation Conditions.” Journal of the Science of Food and Agriculture, vol. 83, No. 4, Mar. 2006, pp. 307-313.
West L.G. et al., “Glucoraphanin and 4-hydroxyglucobrassicin Contents in Seeds of 59 Cultivars of Broccoli, Raab, Kohlrabi, Radish, Cauliflower, Brussels Sprouts, Kale, and Cabbage.” Journal of Agricultural and Food Chemistry, vol. 52, No. 4, 2004, pp. 916-926.
EP Search Report, EP 05106785 (4 pages), 2005.
Cheftel, “Hautes Pressions, Inactivation Microbienne et Conservation des Aliments”,C. R. Acad. Agric. Fr., 1995, 81(1), pp. 13-38.
Mor-Mur et al., “High Pressure Processing Applied to Cooked Sausage Manufacture: Physical Properties and Sensor Analysis”,Meat Science, 2003, 65, pp. 1187-1191.
West et al., “Single Column Approach for the Liquid Chromatographic Separation of Polar and Non-Polar Glucosinolates from Broccoli Sprouts and Seeds”,Journal of Chromatography A.2002, 966, pp. 227-232.
Birthe Bjerg et al., “Isolation Of Intact Glucosinolates By Column Chromatography And Determination Of Their Purity”, Glucosinolates in Rapeseeds: Analytical Aspects, Oct. 1986, pp. 59-75, Martinus Nijhoff a member of the Kluwer Academic Publishers Group, Belgium.
Rita Cortesi, et al., “Hydroxy Propyl Methyl Cellulose Phthalate (HPMCP) Microparticles For Enteric Delivery of Glucosinolate Derived Products From Cruciferous Vegetable”, Minerva Biotecnologica, vol. 12, No. 4, 2000, pp. 293-300.
Frank Desilva et al., “Some Like It Hot, Some Like It Cold”. Published in Water Quality Products Magazine, Aug. 2000, 4 pages.
M.S. Epstein et al., “Determination of Phosphorus in Copper-Based Alloys Using Ion-Exchange Chromatography and Direct-Current Plasma Emission Spectrometry”. Analytical Chemistry, 1987, 59, 2872-2876.
Jed W. Fahey et al., “The Chemical Diversity And Distribution of Glucosinolates And Isothiocyanates Among Plants”, Phytochemistry, 2001, vol. 56, pp. 5-51.
A. Bryan Hanley et al., “Improved Isolation Of Glucobrassicin And Other Glucosinolates”, Journal of Science and Food Agriculture, 1983, vol. 34, pp. 869-873.
Mosbah M. Kushad et al., “Variation of Gluconsinolates in Vegetable Crops of Brassica oleracea”. J. Agricultrual Food Chemistry. 1999. 47, 1541-1548. Simone Rochfort et al., the Isolation and Purification of Glucoraphanin From Broccoli Seeds by Solid Phase.
Simone Rochfort et al., “The Isolation and Purification Of Glucoraphanin From Broccoli Seeds By Solid Phase Extraction A

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Chemoprotectants from crucifer seeds and sprouts does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chemoprotectants from crucifer seeds and sprouts, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chemoprotectants from crucifer seeds and sprouts will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4187302

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.