Substratum having a pattern of cell-culture controlling...

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Solid support and method of culturing cells on said solid...

Reexamination Certificate

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Details

C435S029000, C435S177000, C435S325000, C435S283100

Reexamination Certificate

active

07846727

ABSTRACT:
The present invention relates to a substrate for cell culture capable of controlling at least one function selected from adhesion, proliferation, differentiation, survival, maintenance of undifferentiated state, and apoptosis of a cell. The substrate comprises an immobilization area of controlling substances involved in at least one of the functions of adhesion, proliferation, differentiation, survival, maintenance of undifferentiated state and apoptosis of cells, for example: and the areas are formed by supplying a liquid containing the controlling substances to the substrate by small microdroplet ejection means and immobilizing the controlling substance on the substrate.

REFERENCES:
patent: 5108926 (1992-04-01), Klebe
patent: 6103479 (2000-08-01), Taylor
patent: 6368838 (2002-04-01), Singhvi et al.
patent: 1248108 (1992-10-01), None
patent: WO 97/45730 (1997-12-01), None
Protein, Nucleic Acid and Enzyme, vol. 45, No. 5, pp. 727-734 (2000).
Yoshihiro Ito et al., “Photoimmobilization of Insulin onto Polystyrene Dishes for Protein-Free Cell Culture,” 12(5)Biotechnol. Prog.700-702 (1996).
Ji Zheng, et al., “Growth Enhancement of Anchorage-Dependent and Anchorage-Independent Cells by Coimmobilization of Insulin with Poly(allylamine) or Gelatin,” Biotechnol. Prog., vol. 11, No. 6, pp. 677-681 (1995).
Robert J. Kiebe, “Cytoscribing: A Method for Micropositioning Cells and the Construction of Two- and Three-Dimensional Synthetic Tissues,” Experimental Cell Research, vol. 179, No. 2, pp. 362-373 (1988).
Avri Ben-Ze'ev, et al., “Protein Synthesis Requires Cell-Surface Contact while Nuclear Events Respond to Cell Shape in Anchorage-Dependent Fibroblasts”, Cell, vol. 21, Sep. 1980, pp. 365-372.
Judah Folkman, et al., “Role of cell shape in growth control”, Nature, vol. 273, Jun. 1, 1978, pp. 345-349.
D. Gospodarowicz, et al., “Determination of Cellular Shape by the Extracellular Matrix and Its Correlation with the Control of Cellular Growth”, Cancer Research, vol. 38, Nov. 1978, pp. 4155-4171.
Donald E. Ingber, et al., “Endothelial Growth Factors and Extracellular Matrix Regulate DNA Synthesis Through Modulation of Cell and Nuclear Expansion”, In Vitro Cellular & Developmental Biology, vol. 23, No. 5, May 1987, pp. 387-394.
Yoshihiro Ito, et al., “Enhancement of cell growth on growth factor-immobilized polymer film”, Biomaterials, vol. 12, Jul. 1991, pp. 449-453.

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