Method of treating or preventing osteoporosis using...

Details Method of treating or preventing osteoporosis using... Method of treating or preventing osteoporosis using...

2005-01-27

2010-02-23

Kwon, Brian-Young S (Department: 1614)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

C-o-group doai

C424S195150

Reexamination Certificate

active

07666913

ABSTRACT:
The object of the present invention is to provide a drug effective in treating or preventing osteoporosis. The present invention discloses a therapeutic or preventive drug for osteoporosis having a compound shown in the formula (1)(wherein R1is an alkyloxy group with the carbon number of 1 to 4)or a pharmaceutically acceptable salt or ester of said compound in the formula (1) as an effective ingredient. In the compound of the formula (1), a substance in which R1is CH3O is isotaxiresinol derived fromTaxus yunanennsisand showed physiological activities in inhibiting bone resorption and improving bone formation.

REFERENCES:
patent: 6261565 (2001-07-01), Empie et al.
patent: 6335038 (2002-01-01), Cavazza
patent: 6417224 (2002-07-01), Ohta et al.
patent: 2001/0016590 (2001-08-01), Ahotupa et al.
patent: 2002/0165169 (2002-11-01), Kim et al.
patent: 2003/0144216 (2003-07-01), Unkila
patent: 2005/0158435 (2005-07-01), Abe et al.
patent: 2006/0035964 (2006-02-01), Kadota et al.
patent: 9-12592 (1997-01-01), None
patent: H11-221048 (1999-08-01), None
patent: 2002-518437 (2002-06-01), None
patent: 2003-63971 (2003-03-01), None
patent: 2004-507499 (2004-03-01), None
patent: 99/44621 (1999-09-01), None
patent: 2002/017909 (2002-03-01), None
patent: 2003/075686 (2003-09-01), None
patent: 2004-009065 (2004-01-01), None
Guo et al. (AN: 1994:692369, abstract, Chinese Pharmaceutical Jouranl, 1994, 46(3), 175-83).
Liu et al. (AN 1985:565998, abstract, Taiwan Kexue, 1984, 38(3), 119-25).
Niina M. Saarinen et al.; Uptake and Metabolism of Hydroxymatairesinol in Relation to Its Anticarcinogenicity in DMBA-Induced Rat Mammary Carcinoma Model; Nutrition and Cancer, vol. 41, Nos. 1 & 2, 2001, pp. 82-90. Cited in the ISR.
F. E. King et al.; iso-Taxiresinol* (3′-Demethylisolariciresinol), a New Lignan extracted from the Heartwood of the English Yew,Taxus baccata, J. Chem. Soc., 1952, pp. 17-24. Cited in the spec.
International Search Report dated Mar. 15, 2005 of PCT/JP2005/001055.
Notification of Reason(s) for Refusal, dated Oct. 2, 2009, in corresponding Japanese Application No. 2005-517653.

Affiliated with

Also associated with

Rating

Method of treating or preventing osteoporosis using... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of treating or preventing osteoporosis using..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of treating or preventing osteoporosis using... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4186116