Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Synthesis of peptides
Reexamination Certificate
2006-02-03
2010-02-23
Gtiomer, Ralph (Department: 1657)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Synthesis of peptides
C435S008000
Reexamination Certificate
active
07666987
ABSTRACT:
A sensitive bioluminescent assay to detect proteases including caspases is provided which employs an aminoluciferin or a carboxy-terminal protected derivative thereof covalently linked via a peptide bond to a substrate for a caspase or an aminoluciferin or a carboxy-terminal protected derivative thereof covalently linked via a peptide bond to a peptide substrate comprising aspartate that is specifically cleaved by a protease specific for the substrate.
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Daily William
Klaubert Dieter
O'Brien Martha
Wood Keith V.
Gtiomer Ralph
Michael & Best & Friedrich LLP
Promega Corporation
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