Magnetic resonance imaging methods and apparatus for...

Surgery – Diagnostic testing – Detecting nuclear – electromagnetic – or ultrasonic radiation

Reexamination Certificate

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C600S407000, C600S410000, C324S307000, C324S309000

Reexamination Certificate

active

07835783

ABSTRACT:
Image contributions produced by an untagged specimen magnetization component in magnetic resonance imaging are controlled by applying one or more radiofrequency (RF) pulses that invert at least a portion of the untagged specimen magnetization. In an example, a specimen is tagged with a spatially modulated magnetization that is used to produce an image signal that includes a contribution associated with the tagged magnetization and an untagged magnetization. The untagged magnetization is substantially along an axial direction defined by an applied axial magnetic field. The untagged magnetization increases in magnitude because of so-called T1relaxation. A contribution to the image signal increases for a predetermined time or to a predetermined magnitude, and a 180-degree pulse is applied to invert at least a portion of the untagged magnetization. The untagged magnetization is then antiparallel with respect to the applied axial magnetic field. Additional inversion recovery causes the untagged magnetization to increase from a negative value to zero and then becomes positive. As a result, signal contributions associated with the untagged magnetization are reduced. Additional 180-degree pulses can be applied whenever the untagged magnetization becomes larger than a predetermined value so that image contrast can be maintained. When the tagged magnetization decreases to a predetermined level, an initial specimen magnetization is reestablished for subsequent imaging.

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