Tumor markers for ovarian cancer diagnosis

Details Tumor markers for ovarian cancer diagnosis Tumor markers for ovarian cancer diagnosis

2008-12-02

2010-06-29

Rawlings, Stephen L (Department: 1643)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C530S350000

Reexamination Certificate

active

07745149

ABSTRACT:
The present invention relates to a tumor marker for diagnosis of ovarian cancer, which is selected from the group consisting of galectin-1, cathepsin B, MHC class I antigen, heat shock protein (HSP) 27, ubiquitin carboxy-termal esterase L1, plasma retinol-binding protein (PRBP), transthyretin, SH3 binding glutamate-rich protein, tubulin-specific chaperone A, RNA binding protein regulatory subunit, γ-actin, tropomyosin and calcium/calmodulin-stimulated cyclic nucleotide phosphatase. The ovarian cancer is diagnosed effectively and efficiently based on detecting the expression levels of the tumor markers in the invention from the ovarian tissue sample of an individual to be diagnosed.

REFERENCES:
Brule et al (Lab. Inv., 83(3):377-386, 2003).
Siewinski et al (Bio. Chem., 384:1103-1107, 2003).

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