Antibody-thrombolytic agent product and method of use

Details Antibody-thrombolytic agent product and method of use Antibody-thrombolytic agent product and method of use

1985-01-08

1992-05-26

Doll, John

Drug, bio-affecting and body treating compositions

Lymphokine

435 7021, 4351722, 43524027, 435188, 435212, 435215, 435216, 53038825, 5303917, 5303879, A61K 39395, C07K 1528

Patent

active

051166135

ABSTRACT:
A thrombolytic product comprising a fibrin-specific antibody substantially devoid of fibrinogen cross-reactivity coupled to a thrombolytic agent.

REFERENCES:
patent: 4147765 (1979-04-01), Stephan et al.
patent: 4245040 (1981-01-01), Pilgeram
Pacella, B. L. et al., Molecular Immunol., vol. 20(5):521-528 (1983) cited in Bio. Abstract 7606,9866.
Gaffney, P. J. et al., Haemostasis 10(6):304-311 (1981) cited in Bio. Abstract 74012197.
DeProst, D. et al., Thromb. Haemostasis. 50(4):792-796 (1983) cited in Bio. Abstract 78005612.
Hui et al., Thrombosis and Haemostasis, 54(2):524-527 (1985).
Carrasquillo et al., Radioimmunodetection of Human Melanoma with Monoclonal Antibodies, in Radioimaging and Radioimmunotherapy, Burchiol et al., eds, Elsevier Science, 1983.

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