Use of a PCV2 immunogenic composition for lessening clinical...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

Reexamination Certificate

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Reexamination Certificate

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07838213

ABSTRACT:
The present invention relates to the use of an immunogenic composition that comprises a porcine circovirus type 2 (PCV2) antigen for treatment of several clinical manifestations (diseases). Preferably, the clinical manifestations are associated with a PCV2 infection. Preferably, they include lymphadenopathy, lymphoid depletion and/or multinucleated/giant histiocytes. Moreover, the clinical symptoms include lymphadenopathy in combination with one or a multiple of the following symptoms in pigs: (1) interstitial pneumonia with interlobular edema, (2) cutaneous pallor or icterus, (3) mottled atrophic livers, (4) gastric ulcers, (5) nephritis and (6) reproductive disorders, e.g. abortion, stillbirths, mummies, etc. Furthermore the clinical symptoms include Pia like lesions, normally known to be associated with Lawsonia intracellularis infections.

REFERENCES:
patent: 5322774 (1994-06-01), Peakman
patent: 5565205 (1996-10-01), Petersen
patent: 5580557 (1996-12-01), Kramer
patent: 5733555 (1998-03-01), Chu
patent: 5885823 (1999-03-01), Knittel
patent: 5925359 (1999-07-01), Van Woensel
patent: 5968525 (1999-10-01), Fitzgerald
patent: 6217883 (2001-04-01), Allan
patent: 6287856 (2001-09-01), Poet
patent: 6294176 (2001-09-01), Cochran
patent: 6368601 (2002-04-01), Allan
patent: 6391314 (2002-05-01), Allan
patent: 6497883 (2002-12-01), Bublot et al.
patent: 6517843 (2003-02-01), Ellis
patent: 6660272 (2003-12-01), Allan
patent: 6703023 (2004-03-01), Jestin et al.
patent: 6794163 (2004-09-01), Liu
patent: 6841364 (2005-01-01), Yuan
patent: 6846477 (2005-01-01), Keich
patent: 6943152 (2005-09-01), Audonnet
patent: 6953581 (2005-10-01), Allan
patent: 7018638 (2006-03-01), Chu
patent: 7109025 (2006-09-01), Eloit et al.
patent: 7122192 (2006-10-01), Allan
patent: 7144698 (2006-12-01), Wang
patent: 7148015 (2006-12-01), Jestin
patent: 7169394 (2007-01-01), Chu
patent: 7172899 (2007-02-01), Liu
patent: 7179472 (2007-02-01), Jestin
patent: 7192594 (2007-03-01), Haines
patent: 7211379 (2007-05-01), Ellis
patent: 7223207 (2007-05-01), Basyuk
patent: 7223407 (2007-05-01), Jestin
patent: 7223594 (2007-05-01), Jestin
patent: 7244433 (2007-07-01), Jestin
patent: 7258865 (2007-08-01), Jestin
patent: 7261898 (2007-08-01), Jestin
patent: 7273617 (2007-09-01), Yuan
patent: 7276353 (2007-10-01), Meng
patent: 7279166 (2007-10-01), Meng
patent: 7297537 (2007-11-01), Jestin
patent: 7300785 (2007-11-01), Meerts
patent: 7314628 (2008-01-01), Jestin
patent: 7323330 (2008-01-01), Jestin
patent: 7335361 (2008-02-01), Liao
patent: 7358075 (2008-04-01), Allibert
patent: 7368117 (2008-05-01), Fetzer
patent: 7371395 (2008-05-01), Parisot
patent: 7390494 (2008-06-01), Jestin
patent: 7405075 (2008-07-01), Jestin
patent: 7407803 (2008-08-01), Jestin
patent: 7425444 (2008-09-01), Jestin
patent: 2003/0170270 (2003-09-01), Meng
patent: 2004/0062775 (2004-04-01), Jestin
patent: 2004/0076635 (2004-04-01), Jestin
patent: 2004/0091502 (2004-05-01), Jestin
patent: 2004/0132178 (2004-07-01), Haines
patent: 2004/0161410 (2004-08-01), Jestin
patent: 2004/0253270 (2004-12-01), Meng
patent: 2004/0265848 (2004-12-01), Jestin
patent: 2005/0008651 (2005-01-01), Jestin
patent: 2005/0058653 (2005-03-01), Ellis
patent: 2005/0079185 (2005-04-01), Parisot
patent: 2005/0084497 (2005-04-01), Jestin
patent: 2006/0002952 (2006-01-01), Haines
patent: 2006/0029617 (2006-02-01), Charreyre
patent: 2006/0115489 (2006-06-01), Birkett
patent: 2006/0204522 (2006-09-01), Kroll
patent: 2006/0222659 (2006-10-01), Jestin
patent: 2006/0233831 (2006-10-01), Parisot
patent: 2006/0286123 (2006-12-01), Fetzer
patent: 2007/0196879 (2007-08-01), Chabriere et al.
patent: 2008/0181910 (2008-07-01), Roof
patent: 2008/0233147 (2008-09-01), Jestin
patent: 2008/0261887 (2008-10-01), Roof
patent: 2008/0279875 (2008-11-01), Roof
patent: 2008/0279876 (2008-11-01), Roof
patent: 2008/0279889 (2008-11-01), Roof
patent: 1281760 (2003-02-01), None
patent: 1386617 (2004-02-01), None
patent: 89/06972 (1989-08-01), None
patent: 90/07935 (1990-07-01), None
patent: 91/18627 (1991-12-01), None
patent: 92/03157 (1992-03-01), None
patent: 93/16726 (1993-09-01), None
patent: 95/30437 (1995-11-01), None
patent: 99/18214 (1999-04-01), None
patent: 99/29717 (1999-06-01), None
patent: 99/29871 (1999-06-01), None
patent: 00/47756 (2000-08-01), None
patent: 00/77188 (2000-12-01), None
patent: 01/016330 (2001-03-01), None
patent: 01/17550 (2001-03-01), None
patent: 01/17551 (2001-03-01), None
patent: 01/17556 (2001-03-01), None
patent: 02/49666 (2002-06-01), None
patent: 03/003941 (2003-01-01), None
patent: 2004/058142 (2004-07-01), None
patent: 2004/069184 (2004-08-01), None
patent: 2005/009462 (2005-02-01), None
patent: 2006/072065 (2006-07-01), None
patent: 2006/113372 (2006-10-01), None
patent: 2006/113373 (2006-10-01), None
patent: 2007/028823 (2007-03-01), None
patent: 2007/076520 (2007-07-01), None
Fenaux et al. A Chimeric Porcine Circovirus (PCV) with the Immunogenic Capsid Gene of the Pathogenic PCV Type 2 (PCV2) Cloned into the Genomic Backbone of the Nonpathogenic PCV1 Induces Protective Immunity against PCV2 Infection in Pigs. J Virol. Jun. 2004; 78(12):6297-6303.
Olvera et al. Comparison of porcine circovirus type 2 load in serum quantified by a real time PCR in postweaning multisystemic wasting syndrome and porcine dermatitis and nephropathy syndrome naturally affected pigs. J Virol Meth. 2004; 117:75-80.
Yang, Zong-zhao, A survey on porcine circovirus type 2 infection and phylogenetic analysis of its ORF2 gene in Hangzhou, Zhejiang Province, China, J Zhejiang Univ Sci B. Feb. 2008; 9(2): 148-153.
Does stress-free livestock mean safer food?, http://www.foodnavigator.com/Financial-Industry/Does-stress-free-livestock-mean-safer-food, Jun. 4, 2004.
Vaccination Guidelines For Swine, VIDO Swine Technical Group—Linking knowledge to practical solutions, Vaccination Guidelines, www.vido.org, Jun. 2004.
Albina et al., An Experimental Model for Post-weaning Multisystemic Wasting Syndrome (PMWS)in Growing Piglets, J. Comp. Path., 2001, vol. 123, 292-303.
Allan et al., Experimental infection of colostrum deprived piglets with porcine circovirus 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) potentiates PCV2 replication, Arch. Virol., 2000, 145: 2421-2429.
Allan et al., Porcine circoviruses: a review, J. Vet. Diagn. Invest., 2000, 12:3-14.
Allan et al., Reproduction of postweaning multisystemic wasting syndrome in pigs experimentally inoculated with a Swedish porcine circovirus 2 isolate, 2003, 15:553-560.
Bassaganya-Riera et al., Conjugated Linoleic Acid Ameliorates Viral Infectivity in a Pig Model of Virally Induced Immunosuppression, American Society for Nutritional Sciences, 2003, 3204-3214.
Blanchard et al., Protection of swine against post-weaning multisystemic wasting syndrome (PMWS) by porcine circovirus type 2 (PCV2) proteins, Vaccine 21, 2003, 4565-4575.
Boisseson et al., Molecular characterization of Porcine circovirus type 2 isolates from post-weaning multisystemic wasting syndrome-affected and non-affected pigs, J Gen Virol, 2004, 85, 293-304.
Bolin et al., Postweaning multisystemic wasting syndrome induced after experimental inoculation of cesarean-derived, colostrum-deprived piglets with type 2 porcine circovirus, J Vet Diagn Invest, 2001, 13:185-194.
Chae, C., Postweaning multisystemic wasting syndrome: a review of aetiology, diagnosis and pathology, The Veterinary Journal, 2004, 168:41-49.
Cheung et al., Kinetics of porcine circovirus type 2 replication, Arch Virol, 2002, 147:43-58.
Darwich et al., Cytokine profiles of peripheral blood mononuclear cells from pigs with postweaning multisystemic wasting syndrome in response to mitogen, superantigen or recall viral antigens, J Gen Virol, 2003, 84, 3453-3457.
GenBank Accession No. AAC61738, Version AAC61738.1 GI:3661517, Sep. 29, 1998.
Allan et al., Guest Editorial, PCV-2 infection in swine; more than just postweaning multisystemic wasting syndrome, The Veterinary Journal, 2003, 166:222-223.
Inumaru et al., Expression of biologically active recombinant porcine GM-CSF by baculovirus gene expressio

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