Predicting hepatotoxicity using cell based assays

Details Predicting hepatotoxicity using cell based assays Predicting hepatotoxicity using cell based assays

2006-03-13

2010-10-19

Weber, Jon P (Department: 1657)

Image analysis

Applications

Biomedical applications

C435S040500, C435S019000

Reexamination Certificate

active

07817840

ABSTRACT:
Cell based assays are used to assess the hepatotoxicity of a stimulus. Imaging technologies are used to analyze the effects of a stimulus on hepatocytes. Image analysis may characterize the stimulus on the basis of whether it is hepatotoxic, and if so what type of pathology is exhibited; e.g., apoptosis, necrosis, cholestasis, and/or steatosis.

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