Imidazole-substituted arylamides as P2X 3 and P2X 2/3...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C548S343500

Reexamination Certificate

active

07858654

ABSTRACT:
Compounds of the formula I:wherein R1is optionally substituted imidazolyl, and R2, R3, R4, R5, R6, R7and R8are as defined herein. Also provided are methods of using the compounds for treating diseases mediated by a P2X3and/or a P2X2/3receptor antagonist and methods of making the subject compounds.

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