Glanders/meliodosis vaccines

Details Glanders/meliodosis vaccines Glanders/meliodosis vaccines

2003-07-15

2010-02-23

Navarro, Mark (Department: 1645)

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

C424S093400

Reexamination Certificate

active

07666404

ABSTRACT:
The present invention relates to nucleic acids encodingB. malleiandB. pseudomalleiAHL synthases and LuxR transcriptional regulators, and methods for use, as well as describes the construction, characterization and use of avirulent strains ofB. malleiand methods of use.

REFERENCES:
patent: 6413751 (2002-07-01), Benkovic et al.
DeShazer et al (Microbial Pathogenesis vol. 30, pp. 253-269, May 2001).
Callahan and Dunlap, 2000. LuxR- and acyl-homoserin-lactone-controlled non-luxgenes define a quorum-sensing regulon inVibrio fischeri.J. of Bacteriology 182, 2811-2822.
Nasser, W. et al., 1998. Characterization of theErwinia chrysanthemi expl-expRlocus directing the synthesis of two N-acyl-homoserine lacton signal molecules. Molecular Microbiology 29, 1391-1405.

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