Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-03-26
2010-11-16
Saeed, Kamal A (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S326000, C514S365000, C546S167000, C546S209000, C548S204000
Reexamination Certificate
active
07834030
ABSTRACT:
The present invention comprises phenyl-[1,2,4]-oxadiazol-5-one derivatives of the general formula I:wherein the R1-R10 and B, U, V, W, X, Y and Z substituents are defined herein. The claimed invention also comprises the compounds isomers and their physiologically acceptable salts as well as processes for their preparation. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistance is involved and demyelinating and other neurodegenerative disorders of the central and peripheral nervous system.
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Kulkarni, S.S., et al., Three-Dimensional Quantitative Structure Activity Relationships (3-D-QSAR) of Antihyperglycemic Agents, Bioorganic & Medicinal Chemistry vol. 7, (1999) pp. 1475-1485.
Bernardelli Patrick
Chandross Karen
Glien Maike
Keil Stefanie
Lee Lan
Lin Jiang
Saeed Kamal A
Sanofi-Aventis
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