Production methods of optically active hydrazine compound...

Details Production methods of optically active hydrazine compound... Production methods of optically active hydrazine compound...

2006-01-30

2010-02-02

Davis, Zinna N (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C564S017000, C564S032000

Reexamination Certificate

active

07655817

ABSTRACT:
The present invention relates to a production method of optically active hydrazine compound (IV), which includes reacting azo compound (II) with compound (III) in the presence of optically active compound (I). The present invention also relates to a production method of optically active amine compound (V), which includes producing optically active hydrazine compound (IV) by the above-mentioned method, reacting the optically active hydrazine compound (IV) with a base or an acid to eliminate a protecting group represented by PG, and then subjecting the resulting compound to catalytic reduction or reacting the resulting compound with a zinc powder to reduce a nitrogen-nitrogen bond.wherein X is S or O; C*, C** and C*** are asymmetric carbons, R1and R2are lower alkyl groups etc., R4and R5may in combination form cyclohexane etc., R3is aryl group optionally having substituent(s) etc., R6and R7are hydrogen atoms etc., R8is aryl group optionally having substituent(s) etc., R9and R10are electron withdrawing groups, and PG is a protecting group.

REFERENCES:
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