Polymer for use in conduits, medical devices and biomedical...

Details Polymer for use in conduits, medical devices and biomedical... Polymer for use in conduits, medical devices and biomedical...

2005-01-20

2010-10-26

Peng, Kuo-Liang (Department: 1796)

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

C528S044000, C528S045000, C528S067000, C528S028000

Reexamination Certificate

active

07820769

ABSTRACT:
A copolymer comprising (a) one or more pendant group segments and (b) one or more polyol segments, each of said segments being linked to one or more further segments which may be the same or different,wherein said one or more pendant group segments are the same or different and are selected from:(i) siloxane segments;(ii) segments containing phosphoryl choline or a derivative or analogue thereof;(iii) segments containing a di- or trifluoromethyl group;(iv) heparin-like segments containing a group of formula (XII)in-line-formulae description="In-line Formulae" end="lead"?D-N═N—Ar—SO3−  (XII)in-line-formulae description="In-line Formulae" end="tail"?wherein D is an aliphatic or aromatic group and Ar—SO3−comprises one or more linked aryl and/or heteroaryl groups, at least one of the aryl and/or heteroaryl groups having an SO3−substituent; and(v) segments containing a group of formula (I)in-line-formulae description="In-line Formulae" end="lead"?[P]n′-[Lys]n-Lys-[Spacer]-Lys-[Al]x  (I)in-line-formulae description="In-line Formulae" end="tail"?wherein:[Al] is an inert amino acid;x is 0, 1, 2 or 3;[Spacer] is a fatty acid, amino acid, peptide or PEG;[P]n′-[Lys]nis a dendritic structure formed from n lysine groups and terminating in n′ groups P;n is an integer of from 1 to 15;n′ is zero or an integer of up to 16; andeach P is the same or different and is an amino acid or a peptide having up to 25 amino acids,and wherein at least a part of each of said pendant group segment(s) is on a side chain of the copolymer.The copolymer is useful in the production of implantable devices such as vascular grafts.

REFERENCES:
patent: 4617340 (1986-10-01), Tanaka et al.
patent: 4631329 (1986-12-01), Gornowicz et al.
patent: 4739013 (1988-04-01), Pinchuk
patent: 4839443 (1989-06-01), Akutsu et al.
patent: 4942212 (1990-07-01), Hanada et al.
patent: 5024893 (1991-06-01), Hanada et al.
patent: 5128408 (1992-07-01), Tanaka et al.
patent: 5430121 (1995-07-01), Pudleiner et al.
patent: 5589563 (1996-12-01), Ward et al.
patent: 5863627 (1999-01-01), Szycher et al.
patent: 6313254 (2001-11-01), Meijs et al.
patent: 2002/0028901 (2002-03-01), Gunatillake et al.
patent: 2003/0018156 (2003-01-01), Meijs et al.
patent: 2003/0097120 (2003-05-01), Santerre
patent: 2004/0116641 (2004-06-01), Mather et al.
patent: 2004/0122174 (2004-06-01), Mather et al.
patent: 2004/0122184 (2004-06-01), Mather et al.
patent: 2005/0010275 (2005-01-01), Sahatjian et al.
patent: 0 277 816 (1988-08-01), None
patent: 0 324 946 (1989-07-01), None
patent: 0 416 765 (1991-03-01), None
patent: 04-304224 (1992-10-01), None
patent: 9-194560 (1997-07-01), None
patent: 2006-503170 (2006-01-01), None
patent: 02/098477 (2002-12-01), None
patent: WO 02/098477 (2002-12-01), None
patent: WO 2004/01152 (2004-02-01), None
patent: 2004/032799 (2004-04-01), None
patent: WO 2004/032799 (2004-04-01), None
patent: WO 2004/033515 (2004-04-01), None
Seifalian et al, Tissue Enginnering of Vascular Prosthetic Grafts, 1999 R.G. Landes.
Mohri, H et al, Peptides 1995, 16: p. 263.
Woods, A., et al, Mol. Biol. Cell, 1993; 4: p. 605.
Haverstick, DM et al, Blood; 1985; 66: p. 946.
Freer, R. J., et al, 1979; Peptides, structure and biological function; Proceedings of the sixth American peptide symposium; Gross, E and Meinhofter, M., eds.:749.
Proctor, R.A., Rev. Infect. Dis. 1987; 9: p. 317.
Zhang, H. et al, Biomaterials Mar. 2002; 23(6): 1485-94.
J.P. Tam, Proc. Natl. Sci. USA, 1988, 85, 5409.
H. Rink (1978) Tetrahedron Lett., 28, 3787.
Jaffe et al, J. Clin. Invest. 1973; 52; 2745-56.
Zilla et al, J. Vasc. Sug. 1990; 12: pp. 180-189.
Edwards, A. et al, J. Biomat. App. 1995; 10: pp. 171-187.
WPI abstract AN 1988-142716 [25] & JP 63083121 A.
J.P. Tam; Synthetic Peptides; Approaches to Biological Problems, 3-18 (1989).
D.N. Posnett et al, A novel Method for Producing Anti-Peptide Antibodies; J. Biol. Chem. 263, 1719 (1988).
Fu et al, Polymer 42 (2001) 599-611.
Schwab et al, Mat. Res. Soc. Symp. Proc. 519, Apr. 13, 1998 Materials Research Society, 21-27.
Fan et al, Journal of Applied Polymer Science, vol. 24, 2552-2558 (1999).
Molander et al, Tetrahedron 54 (1998) 9289-9302.
Ward, “Thermoplastic Silicone-Urethane Copolymers: A New Class of Biometical Elastomers”, Medical Device & Diagnostic Industry Magazine, Apr. 2000 (including Table I).
Barry Arkles, Commercial Applications of Sol-Gel-Derived Hybrid Materials, MRS Bulletin, May 2001, 402-408.
Seifalian et al, J. Biomed. Mater. Res. 2001, 55, 637-44.
Aucoin L. et al, J. Miomater. Sci. Polym. Ed., 2002, 13(4):447-62.
Merrett et al, J. Biomed Res. Dec. 1, 2003; 67A(3):981-93.
Li et al, Biomaterials, Oct. 2001 (19):2595-9.
Childs et al, Biomacromolecules, 2001 Summer; 2(2):526-37.
Database WPI, Section Ch, Week 197950, Derwent Publications Ltd., London, GB; AN 1979-90714B & SU 654634 A (Mar. 30, 1979).
International Search Report for PCT/GB2005/000189 dated Jun. 2, 2005.

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