Method and device for monitoring inhibition of platelet...

Chemistry: analytical and immunological testing – Biological cellular material tested

Reexamination Certificate

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C435S008000, C435S288700

Reexamination Certificate

active

07833793

ABSTRACT:
The invention provides a method of monitoring the response of platelets to a COX1 inhibitor such as aspirin. The method involves collecting platelet-containing mammalian blood treated with a COX1 inhibitor; mixing the blood with a COX1-dependent platelet agonist, such as arachidonic acid, monitoring extracellular ATP in the agonist-activated blood to generate a measurement, and comparing the measurement to a standard value. Devices, systems, and kits for carrying out the method are also provided.

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patent: 05772254 (2008-10-01), None
patent: WO 0117649 (2001-03-01), None
patent: WO 2005113800 (2005-12-01), None
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WO2005113800 International Search Report, Dec. 1, 2005, Ericson, Daniel G.

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