Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-02-01
2010-10-26
Saeed, Kamal A (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S135000
Reexamination Certificate
active
07820702
ABSTRACT:
Compounds are provided which are useful in the treatment of androgen receptor-associated conditions, such as age-related diseases, which compounds have the structurewhereinR1, R2, R3, R4, R4a, R4b, R4c, R4c1, Rd, Re, Rf, Rg, Rh, R5, R5′, R7, and R7′are defined herein;G is aryl, heterocycle or heteroaryl group, wherein said group is mono- or polycyclic, and which is optionally substituted; andn is an integer of 1 or 2,m is an integer of 1 or 2,Z is oxygen (—O—) or NR4b,a prodrug ester, all stereoisomers thereof and a pharmaceutically acceptable salt thereof.A method for treating androgen receptor-associated conditions such as age-related diseases is also provided.
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Bi Yingzhi
Hamann Lawrence G.
Manfredi Mark C.
Nirschl Alexandra A.
Sutton James C.
Bristol--Myers Squibb Company
Coppins Janet L
Rodney Burton
Saeed Kamal A
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