Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2004-08-02
2009-06-23
Kosar, Andrew D (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C530S317000
Reexamination Certificate
active
07550431
ABSTRACT:
Novel spatially-defined macrocyclic compounds incorporating peptide bond surrogates are disclosed. Libraries of these macrocycles are then used to select one or more macrocycle species that exhibit a specific interaction with a particular biological target. In particular, compounds according to the invention are disclosed as agonists or antagonists of a mammalian motilin receptor and a mammalian ghrelin receptor.
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Beaubien Sylvie
Deslongchamps Pierre
Dory Yves
Fortin Daniel
Fraser Graeme L.
Kosar Andrew D
Myers Bigel & Sibley Sajovec, PA
Tranzyme Pharma Inc.
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