Processes for the preparation of docetaxel

Details Processes for the preparation of docetaxel Processes for the preparation of docetaxel

2006-06-08

2009-06-23

Andres, Janet L. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C549S511000, C549S214000

Reexamination Certificate

active

07550608

ABSTRACT:
The present invention provides processes for the production of docetaxel. Docetaxel is produced by protecting the C(7) and the C(10) hydroxy groups of 10-DAB with a bridging silicon-based protecting group. The resulting 7,10-protected 10-DAB derivative is then derivatized and deprotected to form docetaxel.

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