Ghrelin o-acyltransferase (GOAT) biochemical assay

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...

Reexamination Certificate

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C435S007500, C435S007900, C435S183000, C435S193000, C536S023200

Reexamination Certificate

active

07544466

ABSTRACT:
Ghrelin is acylated by ghrelin O-acyltransferase. Ghrelin O-acyltransferase assays comprise contacting a mixture of ghrelin and recombinant ghrelin O-acyltransferase with an agent; and detecting a resultant decrease in acylation of the ghrelin by the acyltransferase.

REFERENCES:
patent: WO 2008/079705 (2008-07-01), None
Chica et al. Curr Opin Biotechnol. Aug. 2005;16(4):378-84.
Sen et al. Appl Biochem Biotechnol. Dec 2007;143(3):212-23.

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