Amide derivatives as ion-channel ligands and pharmaceutical...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C546S152000, C546S159000, C514S313000

Reexamination Certificate

active

07576099

ABSTRACT:
Compounds are disclosed that have a formula represented by the following:The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.

REFERENCES:
patent: 3346584 (1967-10-01), Manning et al.
patent: 3424760 (1969-01-01), Helsley et al.
patent: 3424761 (1969-01-01), Helsley et al.
patent: 3798226 (1974-03-01), Kanji et al.
patent: 4393225 (1983-07-01), Hayashi et al.
patent: 4430423 (1984-02-01), Aoki et al.
patent: 4579866 (1986-04-01), Stevenosn et al.
patent: 4642308 (1987-02-01), Cotrel et al.
patent: 4760161 (1988-07-01), Durette et al.
patent: 5559141 (1996-09-01), Karjalainen et al.
patent: 5693672 (1997-12-01), Weichert et al.
patent: 5968946 (1999-10-01), Maryanoff et al.
patent: 6034107 (2000-03-01), Hirai et al.
patent: 6083987 (2000-07-01), Nishino et al.
patent: 6221865 (2001-04-01), Sebti et al.
patent: 6262104 (2001-07-01), Dondio et al.
patent: 6331640 (2001-12-01), Fotouhi et al.
patent: 6414145 (2002-07-01), Boyle et al.
patent: 6486156 (2002-11-01), Arnould et al.
patent: 6656971 (2003-12-01), Wu et al.
patent: 6803384 (2004-10-01), Fotouhi et al.
patent: 6831175 (2004-12-01), Li et al.
patent: 7217728 (2007-05-01), Fotouhi et al.
patent: 7432281 (2008-10-01), Kelly et al.
patent: 2002/0052512 (2002-05-01), Fotouhi et al.
patent: 2002/0165275 (2002-11-01), Wu et al.
patent: 2003/0199511 (2003-10-01), Li et al.
patent: 2003/0220495 (2003-11-01), Boyle et al.
patent: 2004/0006236 (2004-01-01), Fotouhi et al.
patent: 2004/0110802 (2004-06-01), Thorarensen et al.
patent: 2004/0116399 (2004-06-01), Zhu et al.
patent: 2004/0142953 (2004-07-01), DeLorme et al.
patent: 2004/0157919 (2004-08-01), Wu et al.
patent: 2004/0235888 (2004-11-01), Yamamori et al.
patent: 2005/0080119 (2005-04-01), Fotouhi et al.
patent: 2005/0165028 (2005-07-01), Norman et al.
patent: 2005/0222200 (2005-10-01), Kelly et al.
patent: 2006/0020131 (2006-01-01), Raeppel et al.
patent: 2006/0035939 (2006-02-01), Koga et al.
patent: 2006/0111353 (2006-05-01), Weichert et al.
patent: 2006/0154988 (2006-07-01), Andersen et al.
patent: 2006/0194801 (2006-08-01), Kelly et al.
patent: 2007/0099956 (2007-05-01), Kikuchi et al.
patent: 2007/0105943 (2007-05-01), Nakamoto et al.
patent: 2008/0300243 (2008-12-01), Kelly et al.
patent: 2008/0312237 (2008-12-01), Kelly et al.
patent: 2502588 (1976-07-01), None
patent: 0 172 083 (1986-02-01), None
patent: 0 347 000 (1989-12-01), None
patent: 0 401 903 (1990-12-01), None
patent: 2226313 (1990-06-01), None
patent: 11-171848 (1999-06-01), None
patent: 2001-139550 (2001-05-01), None
patent: 2002-055409 (2002-02-01), None
patent: 2005-314347 (2005-11-01), None
patent: WO 92/09285 (1992-06-01), None
patent: WO 96/32015 (1996-10-01), None
patent: WO 97/14681 (1997-04-01), None
patent: WO 97/29079 (1997-08-01), None
patent: WO 97/45402 (1997-12-01), None
patent: WO 97/48694 (1997-12-01), None
patent: WO 98/50029 (1998-11-01), None
patent: WO 98/50030 (1998-11-01), None
patent: WO 98/50031 (1998-11-01), None
patent: WO 99/02497 (1999-01-01), None
patent: WO 99/41235 (1999-08-01), None
patent: WO 99/48492 (1999-09-01), None
patent: WO 00/15213 (2000-03-01), None
patent: WO 00/54759 (2000-09-01), None
patent: WO 00/69849 (2000-11-01), None
patent: WO 01/10380 (2001-02-01), None
patent: WO 01/10381 (2001-02-01), None
patent: WO 01/19798 (2001-03-01), None
patent: WO 01/21160 (2001-03-01), None
patent: WO 01/21615 (2001-03-01), None
patent: WO 01/51456 (2001-07-01), None
patent: WO 01/55115 (2001-08-01), None
patent: WO 01/62737 (2001-08-01), None
patent: WO 01/64642 (2001-09-01), None
patent: WO 01/82916 (2001-11-01), None
patent: WO 02/08221 (2002-01-01), None
patent: WO 02/16317 (2002-02-01), None
patent: WO 02/16318 (2002-02-01), None
patent: WO 02/16319 (2002-02-01), None
patent: WO 02/16517 (2002-02-01), None
patent: WO 02/44126 (2002-06-01), None
patent: WO 02/051397 (2002-07-01), None
patent: WO 02/053101 (2002-07-01), None
patent: WO 02/059080 (2002-08-01), None
patent: WO 02/064547 (2002-08-01), None
patent: WO 02/064568 (2002-08-01), None
patent: WO 02/070494 (2002-09-01), None
patent: WO 02/094766 (2002-11-01), None
patent: WO 03/013516 (2003-02-01), None
patent: WO 03/015774 (2003-02-01), None
patent: WO 03/016254 (2003-02-01), None
patent: WO 03/018536 (2003-03-01), None
patent: WO 03/024448 (2003-03-01), None
patent: WO 03/040174 (2003-05-01), None
patent: WO 03/048101 (2003-06-01), None
patent: WO 03/051366 (2003-06-01), None
patent: WO 03/068749 (2003-08-01), None
patent: WO 2004/002481 (2004-01-01), None
patent: WO 2004/009549 (2004-01-01), None
patent: WO 2004/022536 (2004-03-01), None
patent: WO 2004/024710 (2004-03-01), None
patent: WO 2004/062601 (2004-07-01), None
patent: WO 2004/069792 (2004-08-01), None
patent: WO 2004/096784 (2004-11-01), None
patent: WO 2005/009962 (2005-02-01), None
patent: WO 2005/016277 (2005-02-01), None
patent: WO 2005/019176 (2005-03-01), None
patent: WO 2005/033079 (2005-04-01), None
patent: WO 2005/046683 (2005-05-01), None
patent: WO 2005/115977 (2005-12-01), None
patent: WO 2006/093832 (2006-09-01), None
patent: WO 2007/100758 (2007-09-01), None
Thomas A. Godwin (Gastrointestinal Diseases, <http://edcenter.med.cornell.edu/CUMC—PathNotes/Gastrointestinal/Gastrointestinal.html>, 51 pages),downloaded on Jul. 7, 2005.
Chalmers (TiPS vol. 17, pp. 166-172 Apr. 1996).
ISA/PCT International Search Report dated Jan. 29, 2007, for International Application No. PCT/US2006/006615.
IPEA/PCT International Preliminary Report on Patentability dated May 21, 2007, for International Application No. PCT/US2006/006615.
PCT International Search Report, dated Sep. 28, 2007, for International Application No. PCT/US2007/004912, filed Feb. 22, 2007.
PCT International Preliminary Report on Patentability, dated Oct. 20, 2008, for International Application No. PCT/US2007/004912, filed Feb. 22, 2007.
PCT International Search Report, dated Mar. 28, 2005, for International Application No. PCT/US2004/033163, filed Oct. 7, 2004.
U.S. P.T.O. Non-Final Office Action dated Oct. 16, 2007, in U.S. Appl. No. 10/961,483, filed Oct. 7, 2004.
U.S.P.T.O. Interview Summary between Examiner, Zinna N. Davis, and Rahul Pathak, dated Apr. 21, 2008, in U.S. Appl. No. 10/961,483, filed Oct. 7, 2004.
U.S.P.T.O. Notice of Allowance and Fees Due dated Apr. 24, 2008, in U.S. Appl. No. 10/961,483, filed Oct. 7, 2004.
U.S.P.T.O. Supplemental Notice of Allowability dated Jul. 28, 2008, in U.S. Appl. No. 10/961,483, filed Oct. 7, 2004.
Alonso et al., 1997, “Lithiated 3-Aminoalkyl Sulfones as Mono and Dinucleophiles in the Preparation of Nitrogen Heterocycles: Application to the Synthesis of Capazepine,” Tetrahedron, vol. 53:4791.
Baston et al., 2003 “Cyclohex-1-ene Carboxylic Acids: Synthesis and Biological Evaluation of Novel Inhibitors of Human 5α Reductase,” Arch. Pharm. Pharm. Med. Chem., 1:31-38.
Brisdon et al., “Hydrofluorocarbon 245fa: A Versatile New Synthon in Alkyne Chemistry,” Chem. Comm., 2002, pp. 2420-2421.
Dorsett et al., 1970, “Aminoalkenylbenzenesulfonamides with Hypotensive and Histamine-Releasing Properties,” J. Med. Chem., 13(6):895-900.
Fanta, Paul E., “Sodium Nitromalonaldehyde Monohydrate,” Organic Syntheses, Collective vol. 4, p. 844. ©1963 Organic Synthesis, Inc.
Fu et al., 2002, “Peptidyl Aldehydes as Reversible Covalent Inhibitors of Protein Tyrosine Phosphatases,” Biochemistry, 41:10700-10709.
Hutter et al., “QSAR of Human Steriod 5α-Reductase Inhibitors: Where are the Differences Between Isoenzyme Type 1 and 2?” QSAR Comb. Sci., 23:406-415.
Ikeda et al., 2002, “Cobalt-Catalyzed Heck-Type Reaction of Alkyl Halides with Styrenes,” J. Am. Chem. Soc., 124:6514-6515.
Janusz et al., 1993, Vanilloids. 1. Analogs of Capsacin with Antinociceptive and Antiinflammatory Activity, J. Med. Chem., vol. 36:2595.
Marchand et a

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Amide derivatives as ion-channel ligands and pharmaceutical... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Amide derivatives as ion-channel ligands and pharmaceutical..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amide derivatives as ion-channel ligands and pharmaceutical... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4138296

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.