Peptide identification

Data processing: measuring – calibrating – or testing – Measurement system in a specific environment – Biological or biochemical

Reexamination Certificate

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Reexamination Certificate

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07603240

ABSTRACT:
The present invention provides a peptide identification method along with related peptide databases, method of generating the databases, computer usable media, and computer program products. The peptide identification method involves the use of qualitative amino acid composition or partial qualitative amino acid composition information of a query peptide obtained by mass spectrometry to correlate the query peptide to one or more peptides with defined amino acid sequences in a peptide database generated according to the present invention.

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Role of Accurate Mass Measurement in (+10 ppm) in Protein Identification Strategies Employing MS or MS/MS and Database Searching by Karl R. Clauser, Peter Baker and Alma L. Burlingame, Anal. Chem. 71, 2871-2882, 1999.
Patchwork peptide sequencing: Extraction of sequence information from accurate mass data of peptide tandem mass spectra recorded at high resolution by Andrew Schlosser and Wolf D. Lehmann, Proteomics, 2, 524-533, 2002.
ProMoST (Protein Modification Screening Tool): a web-based tool for mapping protein modifications on two-dimensional gels by Brian D. Halligan, Victor Ruotti, Weihong Jin, Simon N. Twigger and Edward A. Dratz, Nucleic Acid Research 32, W638-W644, 2004.
Peptide Idenfification Using Peptide Amino Acid Attribute Vectors by Brian D. Halligan, Edward A. Dratz, Xin Feng, Simon N. Twigger, Peter J. Tonellato and Andrew S. Green, Journal of Proteome Research 3, 813-820, 2004.
Extended Abstract for the American Society for Mass Spectrometry meeting in Nashville, TN May 23, 2004 by Brian D. Halligan, Andrew S. Greene, Edward A. Dratz., p. 1-2.
Abstract for the American Society for Mass Spectrometry meeting in Nashville, TN May 2004 by Brian D. Halligan, Andrew S. Greene, Edward A. Dratz.
Extended Abstract for the American Society for Mass Spectrometry meeting in Nashville, TN May 23, 2004 by Brian D. Halligan, Andrew S. Greene, Edward A. Dratz.

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