Nano-sized optical fluorescence labels and uses thereof

Details Nano-sized optical fluorescence labels and uses thereof Nano-sized optical fluorescence labels and uses thereof

2003-06-27

2009-11-03

Chin, Christopher L (Department: 1641)

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is inorganic

C436S172000, C436S805000

Reexamination Certificate

active

07611907

ABSTRACT:
A composition is disclosed which is capable of being used for detection, comprising an encapsulated noble metal nanocluster. Methods for preparing the encapsulated noble metal nanoclusters, and methods of using the encapsulated noble metal nanoclusters are also disclosed. The noble metal nanoclusters are preferably encapsulated by a dendrimer or a peptide. The encapsulated noble metal nanoclusters have a characteristic spectral emission, wherein said spectral emission is varied by controlling the nature of the encapsulating material, such as by controlling the size of the nanocluster and/or the generation of the dendrimer, and wherein said emission is used to provide information about a biological state.

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European Supplementary Search Report for EP 03 74 23334 dated Sep. 9, 2008.

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