Freeze-dried product of N-[o-(p-pivaloyloxy...

Details Freeze-dried product of N-[o-(p-pivaloyloxy... Freeze-dried product of N-[o-(p-pivaloyloxy...

2007-04-26

2009-12-29

Oh, Taylor Victor (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

C514S540000, C514S562000, C560S011000, C560S012000, C560S013000, C562S430000

Reexamination Certificate

active

07638556

ABSTRACT:
A method for the preparation of a freeze-dried product of N-[o-(p-pivaloyloxybenzenesulfonylamino)benzoyl]glycine monosodium salt tetra-hydrate dissolved in a mixed solvent of water and ethanol, and the freeze-dried product obtained by the method. According to the present invention, N-[o-(p-pivaloyloxybenzenesulfonylamino)benzoyl]glycine monosodium salt tetra-hydrate is dissolved in a small amount of a mixed solvent of water and ethanol, and therefore it is possible to manufacture high-dosage product by freeze-drying.

REFERENCES:
patent: 5359121 (1994-10-01), Imaki et al.
patent: 6552082 (2003-04-01), Takada et al.
patent: 318146 (1989-05-01), None
patent: 0 347 168 (1989-12-01), None
patent: 539223 (1993-04-01), None
patent: 63-270623 (1988-11-01), None
patent: WO 97/23239 (1997-07-01), None
Patent Abstract of Japan, Feb. 10, 1992, JP040692A (Ono Pharmaceutical Co., Ltd.).

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