Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2007-05-10
2009-11-24
Lewis, Patrick T (Department: 1623)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C514S024000, C514S025000, C514S028000, C536S004100, C536S013000
Reexamination Certificate
active
07622451
ABSTRACT:
Novobiocin analogues and pharmaceutical composition containing such compounds useful for the treatment and/or prevention of neurodegenerative disorders and autoimmune disorders.
REFERENCES:
patent: 6579902 (2003-06-01), Demassey et al.
patent: 2006/0199776 (2006-09-01), Blagg et al.
Shen et al.,Syntheses of photolabile novobiocin analogues, Bioorganic & Medicinal Chemistry Letters 14, 5903-5906 (2004).
Yu et al.,Synthesis of(-)-2,3-O-isopropylidene-D-erythronolactol, J. Org Chem. 69, 7375-7378 (2004).
Yu et al.,Synthesis of Mono- and Dihydroxylated Furanoses, Pyranoses, and an Oxepanose for the Preparation of Natural Product Analogue Libraries, J. Org. Chem. 70, 5599-5605 (2005).
Yu et al.,Hsp90 Inhibitors Identified from a Library of Novobiocin Analogues, J. Am. Chem. Soc. 127, 12778-12779 (2005).
Burlison et al.,Novobiocin: redesigning a DNA Gyrase Inhibitor for Selective Inhibition of Hsp90, J. Am. Chem. Soc., 128 (48), 15529-15536, (2006) (epublished on Nov. 10, 2006).
Blagg Brian
McIntosh Michelle
Michaelis Mary Lou
Lewis Patrick T
Merchant & Gould
University of Kansas
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