Functionally reconstituted viral membranes containing adjuvant

Details Functionally reconstituted viral membranes containing adjuvant Functionally reconstituted viral membranes containing adjuvant

2004-06-18

2009-11-17

Nickol, Gary B (Department: 1648)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

C424S184100, C424S193100, C424S196110, C424S209100, C424S001210, C424S417000, C977S907000

Reexamination Certificate

active

07618641

ABSTRACT:
Vaccines directed against antigens such as membrane proteins from pathogens or tumor cells are disclosed. Also described are methods of forming reconstituted viral membranes, with membrane fusion activity, which are lipid bilayer membranes preferably containing natural lipids of a virus, a viral fusion protein, one or more optional further antigens as well as amphiphilic adjuvants. Pharmaceutical compositions including such reconstituted viral membranes are also described.

REFERENCES:
patent: 4542212 (1985-09-01), Fauve
patent: 5565203 (1996-10-01), Glück et al.
patent: 5879685 (1999-03-01), Glück et al.
patent: 5936076 (1999-08-01), Higa et al.
patent: 6417326 (2002-07-01), Cullis et al.
patent: 2001/0053368 (2001-12-01), Burt et al.
patent: 2003/0092145 (2003-05-01), Jira et al.
patent: 2003/0113347 (2003-06-01), Cusi et al.
patent: 2005/0214359 (2005-09-01), Stegmann
patent: 0109942 (1983-10-01), None
patent: 0180564 (1985-10-01), None
patent: 0205098 (1986-06-01), None
patent: 0231039 (1987-01-01), None
patent: 0487909 (1991-10-01), None
patent: 88/08718 (1988-11-01), None
patent: WO 92/19267 (1992-11-01), None
patent: 02/09746 (2002-02-01), None
Gluck and Metcalfe, Novel approaches in the development of immunopotentiating reconstituted influenza virosomes as efficient antigen carrier systems, 2003, Vaccine, vol. 21, pp. 611-615.
Zurbriggen et al., IRIV-adjuvanted hepatitis A vaccine: in vivo absorption and biophysical characterization, 2000, Progress in Lipid Research, vol. 39, pp. 3-18.
Dijkstra et al., Activation of Murine Lymphocytes by Lipopolysaccharide Incorporated in Fusogenic, Reconstituted Influenza Virus Envelopes (Virosomes), 1996, Journal of Immunology, vol. 157, pp. 1028-1036.
Bron R et al: “Preparation, Properties, and Applications of Reconstituted Influenza Virus Envelopes (Virosomes)” Methods in Enzymology, Academic Press Inc, San Diego, CA, US, vol. 220, 1993, pp. 313-331, XP002915998 ISSN: 0076-6879 p. 330.
Campagnon B et al: “Targeting of Poly (RL)-Poly (RC) by Fusogenic (F Protein) Immunoliposomes” Experimental Cell Research, San Diego, CA, US, vol. 200, No. 2, Jun. 1992, pp. 333-338, XP008005854 ISSN: 0014-4827 p. 334.
Mengiardi B et al: “Virosomes as carriers for combined vaccines” Vaccine, Butterworth Scientific. Guildford, GB, vol. 13, No. 14, Oct. 1, 1995, pp. 1306-1315, XP004057432 ISSN: 0264-410X the whole document.
Fernandes Isabelle et al: “Synthetic lipopeptides incorporated in liposomes: In vitro stimulation of the proliferation of murine splenocytes and in vivo induction of an immune response against a peptide antigen” Molecular Immunology, vol. 34, No. 8-9, Jun. 1997, pp. 569-576, XP002267110 ISSN: 0161-5890 the whole document.
Stegmann T et al: “Functional Reconstitution of Influenza Virus Envelopes” Embo Journal, Oxford University Press, Surrey, GB, vol. 6, No. 9, 1987, pp. 2651-2660, XP009020387 ISSN: 0261-4189 the whole document.

Affiliated with

Also associated with

Rating

Functionally reconstituted viral membranes containing adjuvant does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Functionally reconstituted viral membranes containing adjuvant, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Functionally reconstituted viral membranes containing adjuvant will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4133675