Nanoparticle composite-coated glass microspheres for use in...

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is inorganic

Reexamination Certificate

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C435S005000, C435S006120, C435S007200, C435S007210, C435S007320, C435S007500, C436S525000, C436S527000

Reexamination Certificate

active

07572643

ABSTRACT:
A microsphere for use in a bioassay comprising a glass core coated with a nanoparticle composite comprising a bioactive probe is provided. The nanoparticle composite coating enhances the density of bioprobe loading on the surface of the microspheres, resulting in enhanced dynamic range and sensitivity in bioassays. The particle may be used in detection systems where resonant light scattering properties of the particle are useful.

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