Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2001-10-16
2009-02-10
Landsman, Robert (Department: 1647)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C530S402000
Reexamination Certificate
active
07488795
ABSTRACT:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
REFERENCES:
patent: WO 99/46281 (1999-09-01), None
Skolnick et al. Trends in Biotech. 18:34-39, 2000.
Bork P. Genome Research 10:398-400, 2000.
Doerks et al. Trends in Genetics 14:248-250, 1998.
Smith et al. Nature Biotechnology 15:1222-1223, 1997.
Brenner SE. Trends in Genetics 15:132-133, 1999.
Bork et al. Trends in Genetics 12:425-427, 1996.
Streichert LC, Birnbach CD, Reh TA., J Neurobiol. Jun. 15, 1999;39(4):475-90.
Petters RM et al., Nat Biotechnol. Oct. 1997;15(10):965-70.
Jackson et al.,Eur. J. Immunol. 22(5):1157-1163 (1992).
Clark et al.,Exp. Hematol. 25(8):759 (1997).
Daish et al.,Immunol. 79(1):55-63 (1993).
Clark et al.,Tissue Antigens48:461 (1996).
Ashkenazi, A.J. et al., “PRO Polynucleotides used to produce polypeptides used to target bioactive molecules such as toxins, radiolabels or antibodies, to specific cells, to cause targeted cell death,” GENSEQ Database, Search Date Jan. 15, 2004; Accession No.:P—AAF44269, Pub Date Dec. 7, 2000, GenBank.
Ferrara, N. et al., “Novel PRO polypeptides useful for preventing or rescuing retinal cells from injury caused by ocular diseases such as retinitis pigmentosa, retinopathy, retinal degenerative diseases, degenerative myopia, uveitis,” GENSEQ Database, Search Date Jan. 15, 2004; Accession No.: P—AAA888517, Pub Date Sep. 14, 2000, GenBank.
Ashkenazi, A.J. et al., “PRO Polynucleotides used to produce polypeptides used to target bioactive molecules such as toxins, radiolabels or antibodies, to specific cells, to cause targeted cell death”, GENSEQ Database, Search Date Jan. 15, 2004; Accession No.: P—AAB65300, Pub Date Dec. 7, 2000, Dayhoff.
Ferrara, N. et al., “Novel PRO polypeptides useful for preventing or rescuing retinal cells from injury caused by ocular diseases such as retinitis pigmentosa, retinopathy, retinal degenerative diseases, degenerative myopia, uveitis,” GENSEQ Database, Search Date Jan. 15, 2004; Accession No.: P—AAB19580, Pub Date Sep. 14, 2000, Dayhoff.
Ashkenazi, A.J. et al., “Novel PRO polypeptides and polynucleotides used in detection methods, to target bioactive molecules to specific cells, and to modulate cellular activities,” GENSEQ Database, Search Date Jan. 15, 2004; Accession No.: P—AAB44273, Pub Date Sep. 14, 2000, Dayhoff.
Wood, W.I. et al., “New secreted and transmembrane polypeptides and their polynucleotides, useful for treating blood coagulation disorders, cancers and cellular adhesion disorders,” GENSEQ Database, Search Date Jan. 15, 2004; Accession No.: P—AAY41717, Pub Date Sep. 16, 1999, Dayhoff.
Ashkenazi, A.J. et al., “Novel PRO polypeptides and agonists and antagonists of them, used to diagnose and treat cardiovascular, endothelial and angiogenic disorders,” GENSEQ Database, Search Date Jan. 15, 2004; Accession No.: P—AAB27653, Pub Date Sep. 14, 2000, Dayhoff.
Benjamin, Laura E., et al., “Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: Induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal”, Proc. Natl. Sci. USA, pp. 8761-8766, Aug. 1997.
Bozyczko-Coyne, D., et al., “A rapid fluorometric assay to measure neuronal survival in vitro”, Journal of Neuroscience Methods, vol. 50, pp. 205-216, 1993.
Fontaine, Valérie, et al., “Survival of Purified Rat Photoreceptors In Vitro Is Stimulated Directly by Fibroblast Growth Factor-2”, The Journal of Neuroscience, vol. 18, No. 23, pp. 9662-9672, Dec. 1, 1998.
Fuhrmann, Sabine, et al., “Ciliary neurotrophic factor promotes chick photoreceptor development in vitro”, Development, vol. 121, pp. 2695-2706, 1995.
Jiang, Cheng, et al., “Selenium-Induced Inhibition of Angiogenesis in Mammary Cancer at Chemopreventive Levels of Intake”, Molecular Carcinogenesis, vol. 26, pp. 213-225, 1999.
Levin, Leonard A., et al., “Effect of Lipid Peroxidation Inhibition on Retinal Ganglion Cell Death”, Investigative Ophthalmology & Visual Science, vol. 37, No. 13, Dec. 1996.
Otori, Yasumasa, et al., “Neurotoxic Effects of Low Doses of Glutamate on Purified Rat Retinal Ganglion Cells”, Investigative Ophthalmology & Visual Science, vol. 39, No. 6, May 1998.
Otori, Yasumasa, et al., “Protective effect of nilvadipine against glutamate neurotoxicity in purified retinal ganglion cells”, Brain Research, vol. 961, pp. 213-219, 2003.
Ripps H. “Cell Death in Retinitis Pigmentosa: Gap Junctions and the ‘Bystander’ Effect ” Exp. Eye Res., vol 74 (2002), pp. 327-336.
Farrar G. J., et al. “On the genetics of retinitis pigmentosa and on mutation-independent therapeutic intervention” EMBO J., vol. 21, No. 5 (Mar. 1, 2002), pp. 857-864.
Caminci P et al., Methods in Enzymology, 303: 19-44, 1999.
Goddard Audrey
Godowski Paul J.
Gurney Austin L.
Kljavin Ivar J.
Wood William I.
Barnes Elizabeth M.
De Vry Christopher
Dreger Ginger R.
Genentech Inc.
Landsman Robert
LandOfFree
PRO846 polypeptides does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with PRO846 polypeptides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and PRO846 polypeptides will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4126633