Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-03-07
2009-11-03
Nickol, Gary B (Department: 1646)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C530S387900, C530S399000
Reexamination Certificate
active
07611846
ABSTRACT:
The present invention relates to huXAG-1, huXAG-2 and huXAG-3 proteins which are novel human growth factors. In particular, isolated nucleic acid molecules are provided encoding the huXAG-1, huXAG-2 and huXAG-3 proteins. huXAG-1, huXAG-2 and huXAG-3 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of huXAG-1, huXAG-2 or huXAG-3 activity. Also provided are diagnostic and therapeutic uses of huXAG-1, huXAG-2 and huXAG-3.
REFERENCES:
patent: 5770384 (1998-06-01), Androphy et al.
patent: 5792833 (1998-08-01), Androphy et al.
patent: 6171816 (2001-01-01), Yu et al.
patent: 7060801 (2006-06-01), Yu et al.
patent: WO 96/19566 (1996-06-01), None
patent: WO 98/11217 (1998-03-01), None
patent: WO 98/41627 (1998-09-01), None
patent: WO 98/46756 (1998-10-01), None
patent: WO 99/06548 (1999-02-01), None
Adam, P.J., et al., “Comprehensive Proteomic Analysis of Breast Cancer Cell Membranes Reveals Unique Proteins with Potential Roles in Clinical Cancer,”J. Biol. Chem. 278:6482-6489, The American Society for Biochemistry and Molecular Biology, Inc. (Feb. 2003).
Andersson, B., et al., “A ‘Double Adaptor’ Method for Improved Shotgun Library Construction,”Anal. Biochem. 236:107-113, Academic Press, Inc. (Apr. 1996).
Ausubel, F.M., et al., “Screening Recombinant DNA Libraries,” in:Short Protocols in Molecular Biology, Ausubel, F.M., et al., eds., John Wiley & Sons, Inc., New York, New York, pp. 185-191 (1989).
Callard, R.E. and Gearing, A.J.H., “3. The cytokine network,” in:The Cytokine FactsBook, Callard, R.E. and Gearing, A.J.H., eds., Academic Press, Inc., San Diego, California, pp. 12-17, 119, 185, 214 and 252 (1994).
Database EMBL, Accession No. U76752, Sive, H., et al., European Molecular Biology Laboratory (Dec. 1996).
Database EMBL, Accession No. O42251, Sive, H.L., et al., European Molecular Biology Laboratory (Jan. 1998).
Database EMBL, Accession No. AAY12312, Dumas Milne Edwards, J., et al., European Molecular Biology Laboratory (Jun. 1999).
Database EMBL, Accession No. AAX41145, Dumas Milne Edwards, J., et al., European Molecular Biology Laboratory (Jun. 1999).
Drysdale, T.A. and Elinson, R.P., “Cell Migration and Induction in the Development of the Surface Ectodermal Pattern of theXenopus laevisTadpole,”Develop. Growth&Differ. 34:51-59, Japanese Society of Developmental Biologists (1992).
Fletcher, G.C., et al., “hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan,”Brit. J. Cancer88:579-585, Nature Publishing Group (Feb. 2003).
Folz, R.J., et al., “Substrate Specificity of Eukaryotic Signal Peptidase. Site-Saturation Mutagenesis at Position -1 Regulates Cleavage Between Multiple Sites in Human Pre(ΔPRO)Apolipoprotein A-II,”J. Biol. Chem. 263:2070-2078, The American Society for Biochemistry and Molecular Biology, Inc (1988).
International Search Report for International Patent Application No. PCT/US96/13766, mailed Jan. 7, 1997.
International Search Report for International Patent Application No. PCT/US97/14139, mailed Nov. 17, 1997.
Jamrich, M. And Sato, S., “Differential gene expression in the anterior neural plate during gastrulation ofXenopus laevis,” Development105:779-786, Company of Biologists Ltd. (1989).
Keesee, S.K., et al., “Nuclear matrix proteins in human colon cancer,”Proc. Natl. Acad. Sci. USA91:1913-1916, National Academy of Sciences (1994).
NCBI Entrez, GenBank Report, Accession No. T24475, from Frigerio, J.-M., et al., National Center for Biotechnology Information (Sep. 1994).
NCBI Entrez, GenBank Report, Accession No. T24892, from Frigerio, J.-M., et al., National Center for Biotechnology Information (Sep. 1994).
NCBI Entrez, GenBank Report, Accession No. Z46177, from Auffray, C., et al., National Center for Biotechnology Information (Nov. 1994).
NCBI Entrez, GenBank Report, Accession No. T31098, from Adams, M.D., et al., National Center for Biotechnology Information (Sep. 1995).
NCBI Entrez, GenBank Report, Accession No. T81278, from Hillier, L., et al., National Center for Biotechnology Information (Mar. 1995).
NCBI Entrez, GenBank Report, Accession No. T86663, from Hillier, L., et al., National Center for Biotechnology Information (Mar. 1995).
NCBI Entrez, GenBank Report, Accession No. T94936, from Hillier, L., et al., National Center for Biotechnology Information (Mar. 1995).
NCBI Entrez, GenBank Report, Accession No. T94990, from Hillier, L., et al., National Center for Biotechnology Information (Mar. 1995).
NCBI Entrez, GenBank Report, Accession No. R23553, from Hillier, L., et al., National Center for Biotechnology Information (Apr. 1995).
NCBI Entrez, GenBank Report, Accession No. R46892, from Matsuki, Y., et al., National Center for Biotechnology Information (May 1995).
NCBI Entrez, GenBank Report, Accession No. H35621, from Lee, N.H., et al., National Center for Biotechnology Information (Jul. 1995).
NCBI Entrez, GenBank Report, Accession No. H66313, from Hillier, L., et al., National Center for Biotechnology Information (Oct. 1995).
NCBI Entrez, GenBank Report, Accession No. D75170, from Kohara, Y., et al., National Center for Biotechnology Information (Dec. 1995).
NCBI Entrez, GenBank Report, Accession No. D75830, from Kohara, Y., et al., National Center for Biotechnology Information (Dec. 1995).
NCBI Entrez, GenBank Report, Accession No. D80998, from Fujiwara, T., et al., National Center for Biotechnology Information (Feb. 1996).
NCBI Entrez, GenBank Report, Accession No. W03932, from Hillier, L., et al., National Center for Biotechnology Information (Apr. 1996).
NCBI Entrez, GenBank Report, Accession No. W11310, from Marra, M., et al., National Center for Biotechnology Information (Apr. 1996).
NCBI Entrez, GenBank Report, Accession No. W11794, from Marra, M., et al., National Center for Biotechnology Information (Apr. 1996).
NCBI Entrez, GenBank Report, Accession No. W15466, from Hillier, L., et al., National Center for Biotechnology Information (May 1996).
NCBI Entrez, GenBank Report, Accession No. W37614, from Hillier, L., et al., National Center for Biotechnology Information (May 1996).
NCBI Entrez, GenBank Report, Accession No. W39620, from Hillier, L., et al., National Center for Biotechnology Information (May 1996).
NCBI Entrez, GenBank Report, Accession No. W44207, from Marra, M., et al., National Center for Biotechnology Information (May 1996).
NCBI Entrez, GenBank Report, Accession No. W47880, from Marra, M., et al., National Center for Biotechnology Information (May 1996).
NCBI Entrez, GenBank Report, Accession No. W48140, from Marra, M., et al., National Center for Biotechnology Information (May 1996).
NCBI Entrez, GenBank Report, Accession No. G19689, from Adams, M.D., National Center for Biotechnology Information (May 1996).
NCBI Entrez, GenBank Report, Accession No. G23839 from Hudson, T., National Center for Biotechnology Information (May 1996).
NCBI Entrez, GenBank Report, Accession No. AA030653, from Marra, M., et al., National Center for Biotechnology Information (Aug. 1996).
NCBI Entrez, GenBank Report, Accession No. AA034623, from Marra, M., et al., National Center for Biotechnology Information (Aug. 1996).
NCBI Entrez, GenBank Report, Accession No. AA044518, from Marra, M., et al., National Center for Biotechnology Information (Sep. 1996).
NCBI Entrez, GenBank Report, Accession No. G28839, from Smith, M.W., et al., National Center for Biotechnology Information (Sep. 1996).
NCBI Entrez, GenBank Report, Accession No. W87967, from Marra, M., et al., National Center for Biotechnology Information (Sep. 1996).
NCBI Entrez, GenBank Report, Accession No. W89817, from Marra, M., et al., National Center for Biotechnology Information (Sep. 1996).
NCBI Entrez, GenBank Report, Accession No. C08511, from Koh
Dillon Patrick J.
Ebner Reinhard
Endress Gregory A.
Yu Guo-Liang
Hissong Bruce D
Human Genome Sciences Inc.
Nickol Gary B
Sterne Kessler Goldstein & Fox P.L.L.C.
LandOfFree
Diagnostic methods involving human growth factor huXAG-1 does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Diagnostic methods involving human growth factor huXAG-1, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Diagnostic methods involving human growth factor huXAG-1 will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4125285