Polynucleotide encoding an IL-28A polypepide

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

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C435S069100, C435S070100, C435S325000, C435S471000, C435S320100, C435S810000, C435S975000, C536S023500, C530S351000

Reexamination Certificate

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07629149

ABSTRACT:
Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity.

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