Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2003-10-27
2009-02-24
Jiang, Dong (Department: 1646)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S387100, C530S388100, C530S388150, C530S391300, C530S350000, C435S007100
Reexamination Certificate
active
07495084
ABSTRACT:
The present invention concerns a novel T1R-like ligand II protein. In particular, isolated nucleic acid molecules are provided encoding the T1R-like ligand II protein. T1R-like ligand II polypeptides are also provided, as are recombinant vectors and host cells for expressing the same.
REFERENCES:
patent: 3654090 (1972-04-01), Hermanus et al.
patent: 5576191 (1996-11-01), Gayle et al.
patent: 5767065 (1998-06-01), Mosley et al.
patent: 6130325 (2000-10-01), Goli et al.
patent: WO-94/17187 (1994-08-01), None
Bergers, G. et al., “Alternative promoter usage of the Fos-responsive gene Fit-1 generates mRNA isoforms coding for either secreted or membrane-bound proteins related to the IL-1 receptor,” EMBO J. 13:1176-1188, IRL Press Limited (1994).
Bird, T.A. et al., “Evidence that MAP (Mitogen-Activated Protein) Kinase Activation may be a Necessary but Not Sufficient Signal for a Restricted Subset of Responses in IL-1-Treated Epidermoid Cells,” Cytokine 4:429-440, Academic Press (1992).
Cleary, M.L. et al., “Cloning and Structural Analysis of cDNAs for bcl-2 and a Hybrid bcl-2/Immunoglobulin Transcript Resulting from the t(14;18) Translocation,” Cell 47:19-28, Cell Press (1986).
Eldon, E. et al., “TheDrosphila18 wheeler is required for morphogenesis and has striking similarities to Toll,” Development 120:885-899, Company Of Biologists Limited (1994).
Fleischmann, R.D. et al., “Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd,” Science 269:496-512, Association for the Advancement of Science (Jul. 1995).
Gay, N.J. and F.J. Keith, “DrosophilaToll and IL-1 receptor,” Nature 351:355-356, Macmillian Publishers Ltd. (1991).
Gayle, M.A. et al., “Cloning of a Putative Ligand for the T1/ST2 Receptor,” J. Biol. Chem. 271:5784-5789, American Society for Biochemistry and Molecular Biology, Inc. (Mar. 1996).
Greenfeder, S.A. et al., “Molecular Cloning and Characterization of a Second Subunit of the Interleukin 1 Receptor Complex,” J. Biol. Chem. 270:13757-13765, American Society for Biochemistry and Molecular Biology, Inc. (Jun. 1995).
Hashimoto, C. et al., “The Toll Gene ofDrosophila, Required for Dorsai-Ventral Embryonic Polarity, Appears to Encode a Transmembrane Protein,” Cell 52:269-279, Cell Press (1988).
Hopp, T.P., “Evidence from sequence information that the interleukin-1 receptor is a transmembrane GTPase,” Protein Science 4:1851-1858, Cold Spring Harbor Laboratory Press (Sep. 1995).
Klemenz, R. et al., “Serum- and oncoprotein-mediated induction of a gene with sequence similarity to the gene encoding carcinoembryonic antigen,” Proc. Natl. Acad. Sci. USA 86:5708-5712, National Academy of Sciences of the USA (1989).
Kumar, S. et al., “ST2/T1 Protein Functionally Binds to Two Secreted Proteins from Balb/c 3T3 and Human Umbilical Vein Endothelial Cells but Does Not Bind Interleukin 1,” J. Biol. Chem. 270:27905-27913, American Society for Biochemistry and Molecular Biology, Inc.(Nov. 1995).
Lord, K.A. et al., “Nucleotide sequence and expression of a cDNA encoding MyD88, a novel myeloid differentiation primary response gene induced by IL6,” Oncogene 5:1095-1097, McMillan Press (1990).
Mitcham, J.L. et al., “T1/ST2 Signaling Establishes It as a Member of an Expanding Interleukin-1 Receptor Family,” J. Biol. Chem. 271:5777-5783, American Society for Biochemistry and Molecular Biology, Inc. (Mar. 1996).
Nomura, N. et al., “Prediction of the Coding Sequences of Unidentified Human Genes. I. The Coding Sequences of 40 New Genes (KIAA001-KIAA0040) Deduced by Analysis of Randomly Sampled cDNA Clones from Human Immature Myeloid Cell Line KG-1,” DNA Res. 1:27-35, Kazusa DNA Research Institute And Universal Academy Press (1994).
Ostrowski, J. et al., “A Serine/Threonine Kinase Activity Is Closely Associated with a 65-kDa Phosphoprotein Specifically Recognized by the ?B Enhancer Element,” J. Biol. Chem. 266:12722-12733, American Society for Biochemistry and Molecular Biology, Inc. (1991).
Parnet, P. et al., “IL-1Rrp Is a Novel Receptor-like Molecule Similar to the Type I Interleukin-1 Receptor and Its Homologues T1/ST2 and IL-1R AcP,” J. Biol. Chem. 271:3967-3970, American Society for Biochemistry and Molecular Biology, Inc. (Feb. 1996).
Reikerstorfer, A. et al., “Low Affinity Binding of Interleukin-1β and Intracellular Signaling via NF-?B Identify Fit-1 as a Distant Member of the Interleukin-1 Receptor Family,” J. Biol. Chem. 270:17645-17648, American Society for Biochemistry and Molecular Biology, Inc. (Jul. 1995).
Schneider, D.S. et al., “Dominant and recessive mutations define functional domains of Toll, a transmembrane protein required for dorsal-ventral polarity in theDrosophilaembryo,” Genes & Dev. 5:797-807, Cold Spring Harbor Laboratory Press (1991).
Sims, J.E. et al., “cDNA Expression Cloning of the IL-1 Receptor, a Member of the Immunoglobulin Superfamily,” Science 241:585-589, Association for the Advancement of Science (1988).
Sims, J.E. et al., “Genomic Organization of the Type I and Type II IL-1 Receptors,” Cytokine 7:483-490, Academic Press (Aug. 1995).
Stamnes, M.A. et al., “An Integral Membrane Component of Coatomer-coated Transport Vesicles Defines a Family of Proteins Involved in Budding,” Proc. Natl. Acad. Sci. USA 92:8011-8015, National Academy of Sciences of the USA (Aug. 1995).
Tominaga, S., “A putative protein of a growth specific cDNA from BALB/c-3T3 cells is highly similar to the extracellular portion of mouse interleukin 1 receptor,” FEBS Lett. 258:301-304, Elsevier Science Publishers B.V. (1989).
Yanagisawa, K. et al., “Presence of a novel primary response gene ST2L, encoding a product highly similar to the interleukin 1 receptor type 1,” FEBS Lett. 318:83-87, Elsevier Science Publishers B.V. (1993).
S. Vukicevic et al., “Induction of nephrogenic mesenchyme by osteogenic protein 1 (bone morphogenetic protein 7,” Proc. Natl. Acad. Sci. USA, 93:9021-9026 (1996).
J. Skolnick et al., “From genes to protein structure and function: novel applications of computational approaches in the genomic era,” Trends in Biotechnology 18(1):34-39 (2000).
T. Doerks et al., “Protein annotation: detective work for function prediction,” Trends in Genetics 14(6):248-250 (1998).
T.F. Smith et al., “The challenges of genome sequence annotation or ‘the devil is in the details’,” Nature Biotech. 15:1222-1223 (1997).
Gentz Reiner L.
Ni Jian
Ruben Steven M.
Human Genome Sciences Inc.
Jiang Dong
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