Immunization of an individual against carcinomas and the...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C424S277100

Reexamination Certificate

active

07569538

ABSTRACT:
The present invention relates to a pharmaceutical composition, comprising a cell cycle regulatory protein and/or an expressible nucleic acid coding for this in an amount suitable for immunization of an individual against carcinomas and the preliminary stages thereof and common auxiliary agents and/or to the use of a cell cycle regulatory protein and/or an expressible nucleic acid coding for this to immunize an individual against carcinomas and the preliminary stages thereof.

REFERENCES:
patent: 5733920 (1998-03-01), Mansuri et al.
patent: DE 198 29 473 (2000-01-01), None
patent: WO 98 45444 (1998-10-01), None
patent: WO 99 02183 (1999-01-01), None
patent: WO 99/19357 (1999-04-01), None
Trisha Gura, “Systems for Identifying New Drugs are Often Faulty”, Science, vol. 278, pp. 1041-1042, Nov. 7, 1997.
Matteo Bellone et al., “Cancer Immunotherapy: Synthetic and Natural Peptides in the Balance”, Immunology Today, vol. 20, No. 10, pp. 457-461, Oct. 1999.
Alexander Gaiger et al., “Immunity to WT1 in the Animal Model and in Patients With Acute Myeloid Leukemia”, Blood, vol. 6, No. 4, pp. 1480-1489, Aug. 15, 2000.
R. Ian Freshney, “Culture of Animal Cells”, A Manual of Basic Technique, Alan R. Liss, Inc., New York, p. 4, 1983.
Gerald B. Dermer, “Another Anniversary for the War on Cancer”, Bio/Technology, vol. 12, pp. 320, Mar. 1994.
J. H. Carter et al., “Cycling—an Overexpressed Cell Cycle Protein as a Potential Tumour Antigen Target for Immunotherapy”, Immunology, vol. 95, No. Suppl. 1, pp. 104, Dec. 1998.

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