Process for the preparation of finasteride Form I

Details Process for the preparation of finasteride Form I Process for the preparation of finasteride Form I

2004-07-05

2009-06-23

Aulakh, Charanjit S (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S061000

Reexamination Certificate

active

07550593

ABSTRACT:
A process of preparing finasteride Form (I), which process comprises dissolving finasteride in a solvent, replacing the solvent partially or substantially completely with a nonsolvent and thereafter isolating finasteride Form (I). There is also provided finasteride Form (I) prepared in accordance with the present invention, and the therapeutic use thereof in the inhibition of 5-alpha reductase, and pharmaceutical compositions containing the same.

REFERENCES:
patent: 4760071 (1988-07-01), Rasmusson et al.
patent: 5652365 (1997-07-01), McCauley et al.
patent: 5670643 (1997-09-01), Davis et al.
patent: 0599376 (1994-06-01), None
patent: 0132683 (2001-05-01), None
patent: 2004 039828 (2004-05-01), None
US2002/0042425, Abstract, Inventor Gormley, Glenn J; Transdermal treatment with 5-alpha reductase inhibitors.

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