Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2004-04-14
2009-11-10
Kapushoc, Stephen (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S091200, C536S024300, C536S024330, C204S403030
Reexamination Certificate
active
07615343
ABSTRACT:
The invention relates to the detection of the binding of analyte molecules, for example biopolymer molecules, to immobilized capture substance molecules. The invention consists in using semiconductor wafers (chips) with electrical circuits in spatial proximity to a surface area coated with capture substance molecules and loading the binding of the analyte molecules to the capture substance molecules with co-bound electrically conductive nanoparticles so that the nanoparticles can act upon the electrical circuits either through changes in the electrical stray capacitance or by generating electric currents, thus making the binding of the analyte molecules electronically detectable.
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Baum Hans-Jakob
Franzen Jochen
Bruker Daltonik GmbH
Kapushoc Stephen
Law Offices of Paul E. Kudirka
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