Process for preparation of paricalcitol and intermediates...

Details Process for preparation of paricalcitol and intermediates... Process for preparation of paricalcitol and intermediates...

2007-12-10

2009-02-17

Witherspoon, Sikarl A (Department: 1621)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

9,10-seco- cyclopentanohydrophenanthrene ring system doai

C514S653000, C552S653000

Reexamination Certificate

active

07491712

ABSTRACT:
The invention relates to a novel process for the preparation of Paricalcitol and intermediates thereof.

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Coutts et al., A Stereospecific Synthesis of 24(S)-Hydroxyvitamin D2, a Prodrug for 1.alpha.,24(S)-Dihydroxyvitamin D2, Organic Process Research & Development (2002), 6(3), 246-255.
Herbert E. Paaren et al.,; Electrophilic Addition of OsO4 to 25-Hydroxycholecaliferol and Its 3,5-Cyclo Derivative; Journal;1983; pp. 3819-3821; vol. 48, No. 21; Journal of Organic Chemistry; American Chemical Society.
Lisa D. Coutts et al.,; A Stereospecific Synthesis of 24(S)-Hydroxyvitamin D2 . . . ; Journal; 2002; pp. 246-255; vol. 6, No. 3; Organic Process Research & Development; American Chemical Society.

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