Promoter variants of the alpha-7 nicotinic acetylcholine...

Details Promoter variants of the alpha-7 nicotinic acetylcholine... Promoter variants of the alpha-7 nicotinic acetylcholine...

2003-11-26

2009-08-11

Ulm, John D (Department: 1649)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

Reexamination Certificate

active

07572580

ABSTRACT:
The present invention is directed to methods and compositions related to α7 acetylcholine nicotinic receptor genes, in particular, the human α7 nicotinic acetylcholine receptor gene. The human α7 nicotinic acetylcholine receptor gene is associated with the pathophysiological aspects of the disease schizophrenia. The present invention further provides methods and compositions to screen populations for abnormal α7 alleles, as well as methods and compositions for development of therapeutics.

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