Surgery – Diagnostic testing – Detecting nuclear – electromagnetic – or ultrasonic radiation
Reexamination Certificate
2007-07-29
2009-10-13
Le, Long V (Department: 3768)
Surgery
Diagnostic testing
Detecting nuclear, electromagnetic, or ultrasonic radiation
C600S407000, C600S425000, C600S431000, C600S438000, C600S476000, C250S363010
Reexamination Certificate
active
07603167
ABSTRACT:
The present invention provides systems and methods for obtaining a three-dimensional (3D) representation of one or more light sources inside a sample, such as a mammal. Mammalian tissue is a turbid medium, meaning that photons are both absorbed and scattered as they propagate through tissue. In the case where scattering is large compared with absorption, such as red to near-infrared light passing through tissue, the transport of light within the sample is described by diffusion theory. Using imaging data and computer-implemented photon diffusion models, embodiments of the present invention produce a 3D representation of the light sources inside a sample, such as a 3D location, size, and brightness of such light sources.
REFERENCES:
patent: 4687325 (1987-08-01), Corby, Jr.
patent: 4687352 (1987-08-01), Igi et al.
patent: 4761071 (1988-08-01), Baron
patent: 4773097 (1988-09-01), Suzaki et al.
patent: 5202091 (1993-04-01), Lisenbee
patent: 5205291 (1993-04-01), Potter
patent: 5242441 (1993-09-01), Avitall
patent: 5319209 (1994-06-01), Miyakawa et al.
patent: 5334193 (1994-08-01), Nardella
patent: 5414258 (1995-05-01), Liang
patent: 5452723 (1995-09-01), Wu et al.
patent: 5584872 (1996-12-01), LaFontaine et al.
patent: 5594253 (1997-01-01), Bueno et al.
patent: 5636299 (1997-06-01), Bueno et al.
patent: 5637874 (1997-06-01), Honzawa et al.
patent: 5650135 (1997-07-01), Contag et al.
patent: 5661562 (1997-08-01), Aharon
patent: 5672881 (1997-09-01), Striepeke et al.
patent: 5705807 (1998-01-01), Throngnumchai
patent: 5738101 (1998-04-01), Sappey
patent: 5746210 (1998-05-01), Benaron et al.
patent: 5807262 (1998-09-01), Papaioannou et al.
patent: 5812310 (1998-09-01), Stewart et al.
patent: 5818587 (1998-10-01), Devaraj et al.
patent: 5835617 (1998-11-01), Ohta et al.
patent: 5840572 (1998-11-01), Copeland
patent: 5865754 (1999-02-01), Sevick-Muraca et al.
patent: 5867250 (1999-02-01), Baron
patent: 5917190 (1999-06-01), Yodh et al.
patent: 5943129 (1999-08-01), Hoyt et al.
patent: 5953446 (1999-09-01), Opsal et al.
patent: 5963658 (1999-10-01), Klibanov et al.
patent: 5970164 (1999-10-01), Bamberger
patent: 6069698 (2000-05-01), Ozawa et al.
patent: 6108576 (2000-08-01), Alfano et al.
patent: 6175407 (2001-01-01), Sartor
patent: 6205347 (2001-03-01), Morgan et al.
patent: 6208886 (2001-03-01), Alfano et al.
patent: 6217847 (2001-04-01), Contag et al.
patent: 6219566 (2001-04-01), Weersink et al.
patent: 6242743 (2001-06-01), DeVito et al.
patent: 6252623 (2001-06-01), Lu et al.
patent: 6264610 (2001-07-01), Zhu
patent: 6267477 (2001-07-01), Karpol et al.
patent: 6321111 (2001-11-01), Perelman et al.
patent: 6332087 (2001-12-01), Svenson et al.
patent: 6364829 (2002-04-01), Fulghum
patent: 6373557 (2002-04-01), Mengel et al.
patent: 6373568 (2002-04-01), Miller et al.
patent: 6377353 (2002-04-01), Ellis
patent: 6381302 (2002-04-01), Berestov
patent: 6392241 (2002-05-01), Rushbrooke et al.
patent: 6394965 (2002-05-01), Klein
patent: 6403947 (2002-06-01), Hoyt et al.
patent: 6415051 (2002-07-01), Callari et al.
patent: 6429943 (2002-08-01), Opsal et al.
patent: 6529627 (2003-03-01), Callari et al.
patent: 6549288 (2003-04-01), Migdal et al.
patent: 6597931 (2003-07-01), Cheng et al.
patent: 6615061 (2003-09-01), Khalil et al.
patent: 6615063 (2003-09-01), Ntziachristos
patent: 6618152 (2003-09-01), Toida
patent: 6618463 (2003-09-01), Schotland et al.
patent: 6628401 (2003-09-01), Toida
patent: 6628747 (2003-09-01), Schotland et al.
patent: 6636755 (2003-10-01), Toida
patent: 6642953 (2003-11-01), Nieto Velasco et al.
patent: 6646678 (2003-11-01), Kobayashi
patent: 6665072 (2003-12-01), Hoyt
patent: 6690466 (2004-02-01), Miller et al.
patent: 6690520 (2004-02-01), Kusuzawa
patent: 6693710 (2004-02-01), Hoyt
patent: 6710770 (2004-03-01), Tomasi et al.
patent: 6750964 (2004-06-01), Levenson et al.
patent: 6775349 (2004-08-01), Schotland et al.
patent: 6775567 (2004-08-01), Cable et al.
patent: 6813030 (2004-11-01), Tanno
patent: 6919919 (2005-07-01), Nelson et al.
patent: 6924893 (2005-08-01), Oldenbourg et al.
patent: 6963375 (2005-11-01), Lundberg
patent: 7113217 (2006-09-01), Nilson et al.
patent: 7184047 (2007-02-01), Crampton
patent: 7263157 (2007-08-01), Bruder et al.
patent: 2003/0002028 (2003-01-01), Rice et al.
patent: 2003/0099329 (2003-05-01), Schotland et al.
patent: 2004/0001080 (2004-01-01), Fowkes et al.
patent: 2004/0010192 (2004-01-01), Benaron et al.
patent: 2004/0015062 (2004-01-01), Ntziachristos et al.
patent: 2004/0021771 (2004-02-01), Stearns et al.
patent: 2004/0027659 (2004-02-01), Messerschmidt et al.
patent: 2004/0085536 (2004-05-01), Schotland et al.
patent: 2004/0262520 (2004-12-01), Schotland et al.
patent: 2005/0149877 (2005-07-01), Rice et al.
patent: 2005/0283071 (2005-12-01), Ripoll et al.
patent: 2006/0118742 (2006-06-01), Levenson et al.
patent: 2006/0119865 (2006-06-01), Hoyt et al.
patent: 2006/0146346 (2006-07-01), Hoyt
patent: 2006/0173354 (2006-08-01), Ntziachristos et al.
patent: 2006/0203244 (2006-09-01), Nilson et al.
patent: 2006/0245631 (2006-11-01), Levenson
patent: 2006/0268153 (2006-11-01), Rice et al.
patent: 2007/0016078 (2007-01-01), Hoyt et al.
patent: 1 016 419 (2000-07-01), None
patent: 06-129984 (1994-05-01), None
patent: 08-136448 (1996-05-01), None
patent: 11-173976 (1999-07-01), None
patent: 96/16596 (1996-06-01), None
patent: WO97/40381 (1997-10-01), None
patent: WO98/34533 (1998-08-01), None
patent: WO 00/17643 (2000-03-01), None
patent: WO00/36106 (2000-06-01), None
patent: WO00/54581 (2000-09-01), None
patent: WO01/18225 (2001-03-01), None
patent: WO01/63247 (2001-08-01), None
patent: WO02/41760 (2002-05-01), None
Achilefu et al., “Novel Receptor-Targeted Fluorescent Contrast Agents for In Vivo Tumor Imaging”, Investigative Radiology, vol. 35(8), Aug. 200, pp. 479-485.
Arridge, “Photon-Measurement Density Functions. Part 1: Analytical Forms”, Applied Optics, vol. 34, No. 31, Nov. 1, 1995, pp. 7395-7409.
Arridge, “Photon-Measurement Density Functions. Part 2: Finite-Element-Method Calculations”, Applied Optics, vol. 34, No. 34, Dec. 1, 1995, pp. 8026-8037.
Becker et al., “receptor-Targeted Optical Imaging of Tumors with Near-Infrared Fluorescent Ligands”, Nature Biotechnology, vol. 19, Apr. 2001, pp. 327-330.
Benaron, David A., “A System for Imaging Infection and Gene Expression in the Body in 3-D,” Biomedical Optical Spectroscopy and Diagnostics, 1998 Technical Digest, 1998, Optical Society of America, pp. 134-135.
Bevilacqua et al., “In Vivo Local Determination of Tissue Optical Properties: Applications to Human Brain”, Applied Optics, vol. 38, No. 22, Aug. 1, 1999, pp. 4939-4950.
Bevilacqua et al., “Monte Carlo Study of Diffuse Reflectance at Source-Detector Separations Close to One Transport Mean Free Path”, Optical Society of America, vol. 16, No. 12, Dec. 1999, pp. 2935-2945.
Bouvet et al., “Real-Time Optical Imaging of Primary Tumor Growth and Multiple Metastatic Events in a Pancreatic Cancer Orthotopic Model”, Cancer Research, vol. 62, Mar. 1, 2002, pp. 1534-1540.
Chang et al., “Improved Reconstruction Algorithm for Luminescence Optical Tomography When Background Lumiphore is Present”, Applied Optics, vol. 37, No. 16, Jun. 1, 1998, pp. 3547-3552.
Cheong et al., “A review of the Optical Properties of Biological Tissues”, IEEE Journal of Quantum Electronics, vol. 26, No. 12, Dec. 1990, pp. 2166-2185.
Contag et al., “Photonic Detection of Bacterial Pathogens in Living Hosts”, Molecular Microbiology, vol. 18, No. 4, 1995, pp. 593-603.
Contag et al., “Use of Reporter Genes for Optical Measurements of Neoplastic Disease In Vivo”, Neoplasia, vol. 2, Nos. 1-2, Jan.-Apr. 2000, pp. 41-52.
Eppstein et al., “Biomedical Optical Tomography Using Dynamic Parameterization and Bayesian Conditioning on Photon Migration Measurements”, Applied Optics, vol. 38, No. 10, Apr. 1, 1999, pp. 2138-2150.
Francis et al, “Visualizing Pneumococcal Infections in t
Cable Michael D.
Rice Bradley W.
Stearns Daniel G.
Beyer Law Group LLP
Gupta Vani
Le Long V
Xenogen Corporation
LandOfFree
Method and apparatus for 3-D imaging of internal light sources does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method and apparatus for 3-D imaging of internal light sources, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and apparatus for 3-D imaging of internal light sources will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4103615