Methods for manipulating satiety

Details Methods for manipulating satiety Methods for manipulating satiety

2006-07-13

2009-10-27

Swartz, Rodney P. (Department: 1645)

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Testing efficacy or toxicity of a compound or composition

C424S009100, C424S116000, C424S278100, C424S439000, C426S002000, C426S071000, C426S658000, C426S800000, C426S801000, C435S004000, C435S029000

Reexamination Certificate

active

07608245

ABSTRACT:
Disclosed is a method of manipulating the rate of upper gastrointestinal transit of a substance in a mammal. Also disclosed are methods of manipulating satiety and post-prandial visceral blood flow. A method of treating visceral pain or visceral hypersensitivity in a human subject is also described. A method for prolonging the residence time of an orally or enterally administered substance by promoting its dissolution, bioavailability and/or absorption in the small intestine is also described. These methods are related to a method of transmitting to and replicating at a second location in the central nervous system a serotonergic neural signal originating at a first location in the proximal or distal gut of a mammal and/or a method of transmitting to and replicating at a second location in the upper gastrointestinal tract a serotonergic neural signal originating at a first location in the proximal or distal gut.

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