N-(naphthylethyl)imidazole derivatives

Details N-(naphthylethyl)imidazole derivatives N-(naphthylethyl)imidazole derivatives

1978-06-19

1979-10-23

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

548341, C07D23360, A61K 31415

Patent

active

041721411

ABSTRACT:
Compounds of the formula ##STR1## wherein R is alkyl, benzyl, substituted benzyl, phenyl or substituted phenyl, said substituted benzyl and substituted phenyl substituted on the phenyl ring with from one to three substituents independently selected from the group consisting of halo, lower alkyl and trifluoromethyl; X is oxygen or sulfur; and the pharmaceutically acceptable acid addition salts thereof are CNS-active agents, inhibitors of gastric secretion and antifungal, antibacterial and antiprotozoal agents.

REFERENCES:
patent: 3575999 (1971-04-01), Godefroi et al.
patent: 3658813 (1972-04-01), Godefroi et al.
patent: 3717655 (1973-02-01), Godefroi et al.
patent: 3755349 (1973-08-01), Timmler et al.
patent: 3764690 (1973-10-01), Draber et al.
patent: 3796704 (1974-03-01), Metzger et al.
patent: 3812142 (1974-05-01), Meiser et al.
patent: 3839574 (1974-10-01), Godefroi et al.
Godefroi et al., J. Med. Chem. 1969, vol. 12, pp. 784-790.
Baggaley et al. J. Chem. Soc. (London) Perkin trans. 1 1975, pp. 1670-1671.

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